Actively Recruiting

All Genders
NCT07051083

Bladder Cancer Staging and Prediction of New Adjuvant Chemotherapy Efficacy Based on Deep Learning and Transfer Learning in Ultrasound-Magnetic Resonance-Pathology Multimodal Multiscale

Led by Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University · Updated on 2025-07-03

480

Participants Needed

1

Research Sites

156 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Bladder cancer is the most common malignant tumor of the urinary system. The presence or absence of muscle invasion in early bladder cancer is an independent prognostic factor. The involvement of muscle invasion affects the choice of surgical methods and treatment. Preoperatively, the precise assessment of bladder cancer staging has important practical value. A more accurate preoperative assessment of bladder cancer staging can reduce overtreatment and provide a favorable basis for clinicians to choose more reasonable and effective surgical methods. Clinically, there has been a longstanding desire to diagnose the staging of bladder cancer through a simple, convenient, effective, and non-invasive examination. As relevant research progresses, a multi-omics diagnostic model will be beneficial in improving diagnostic efficiency. This project aims to establish a multi-omics artificial intelligence system based on deep learning and transfer learning to accurately diagnose the staging of bladder cancer and predict the efficacy of neoadjuvant chemotherapy. This system will assist in clinical treatment decision-making.

CONDITIONS

Official Title

Bladder Cancer Staging and Prediction of New Adjuvant Chemotherapy Efficacy Based on Deep Learning and Transfer Learning in Ultrasound-Magnetic Resonance-Pathology Multimodal Multiscale

Who Can Participate

All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Ultrasound or other imaging tests (CT, MR) suggest bladder masses suspicious for bladder cancer
  • Bladder is well filled and no allergy to ultrasound contrast agents
  • No prior surgery, radiotherapy, or chemotherapy performed
  • Planned for surgical treatment with at least one of the following: clinical symptoms like gross hematuria, confirmed primary or recurrent bladder cancer by cystoscopic biopsy, or urine tests suggesting malignancy
Not Eligible

You will not qualify if you...

  • Unable to tolerate surgery
  • Allergic to ultrasound contrast agents and unable to undergo contrast examination
  • Unsuccessful or non-compliant preoperative ultrasound contrast examination
  • Postoperative pathology does not indicate bladder cancer
  • Prior chemotherapy or radiation therapy received

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Sun Yat-sen Memorial Hospital, Sun Yat-sen University

Guangzhou, Guangdong, China, 510288

Actively Recruiting

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Research Team

Q

Qiyun Ou, Dr.

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

3

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