Actively Recruiting

All Genders
ID05430971

Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN) International Registry

Led by Immune Oncology Research Institute · Updated on 2026-06-05

200

Participants Needed

22

Research Sites

N/A

Total Duration

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AI-Summary

What this Trial Is About

Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN) is a very rare blood cancer with no agreed-upon best treatment. Researchers are working internationally to gather detailed information on how BPDCN presents, how it is diagnosed, the treatments patients receive, and their outcomes. The study aims to build a large database to better understand the disease and to develop treatment recommendations based on collected data. This study is an international registry collecting information from multiple centers about patients diagnosed with BPDCN. It includes both retrospective and prospective data from patients worldwide. The data collected covers patient details, disease characteristics, treatment information, outcomes, causes of death, and the conclusion of data collection. Consent will be obtained from prospective patients, and quality control is managed by the Immune Oncology Research Institute. Participants will provide information through questionnaires completed by their treatment centers. Researchers will analyze overall survival, complete remission rates, duration of first remission, and event-free survival over five years. This observational study does not involve treatment but gathers and monitors detailed clinical data to improve understanding and guide future therapies for BPDCN.

CONDITIONS

Brief Title

Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN) International Registry

Who Can Participate

All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Diagnosis of BPDCN
  • Signed informed consent form for prospective patients
Not Eligible

You will not qualify if you...

History of severe allergic reactions to study medication Currently pregnant or breastfeeding Recent participation in another clinical trial within the last 30 days Presence of uncontrolled medical conditions that could affect safety

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

Monitoring

Duration - Up to 5 years

Participants who have been diagnosed with BPDCN are observed to collect data on patient characteristics, treatment details, outcomes, and survival over time.

Trial Site Locations

Total: 22 locations

1

Sylvester Comprehensive Cancer Center, University of Miami

Miami, Florida, United States, 33136

Actively Recruiting

2

Moffitt Cancer Center

Tampa, Florida, United States, 33612

Actively Recruiting

3

Seattle Children's Cancer and Blood Disorders Center

Seattle, Washington, United States, 98145

Actively Recruiting

4

Hematology Center named after prof. R. Yeolyan

Yerevan, Armenia, 0014

Actively Recruiting

5

University of Calgary

Calgary, Alberta, Canada, T2N 1N4

Actively Recruiting

6

Children's Hospital of Eastern Ontario, University of Ottawa

Ottawa, Ontario, Canada, K1H 8L1

Actively Recruiting

7

Cyprus Society of Haematology

Nicosia, Cyprus, 2019

Actively Recruiting

8

Oncology Center, Mansoura University Faculty of Medicine

Al Mansurah, Egypt, 7650030

Actively Recruiting

9

M. Iashvili Children's Central Hospital

Tbilisi, Georgia, 0159

Actively Recruiting

10

Department of Medical Oncology, Dr. B.R.A Institute Rotary Cancer Hospital, All India Institute of Medical Sciences

New Delhi, India, 110029

Actively Recruiting

11

Pediatric Hematology Oncology, Children's Welfare Teaching Hospital, Medical City, College of Medicine, University of Baghdad

Baghdad, Iraq, 61023

Actively Recruiting

12

University of Perugia - Azienda Ospedaliera Perugia

Perugia, Italy, 06129

Actively Recruiting

13

Department of Biomedicine and Prevention, University of Rome Tor Vergata

Roma, Italy, 00133

Actively Recruiting

14

King Hussein Cancer Center (KHCC)

Amman, Jordan, 11941

Actively Recruiting

15

Department of hematology, Kuwait Cancer Control Center

Kuwait City, Kuwait, 42262

Actively Recruiting

16

Fundeni Clinical Institute, Department of Acute Leukemia

Bucharest, Romania, 022328

Actively Recruiting

17

China Medical University Children's Hospital

Taichung, Taiwan, 40447

Actively Recruiting

18

Turkish Pediatric Cancer Registry

Ankara, Turkey (Türkiye), 06690

Actively Recruiting

19

Istanbul University, Oncology Institute

Istanbul, Turkey (Türkiye), 34093

Actively Recruiting

20

University of Health Sciences, Umraniye Research and Education Hospital, Pediatric Hematology and Oncology Department, Pediatric Bone Marrow Transplantation Unit

Istanbul, Turkey (Türkiye), 34766

Actively Recruiting

21

Broomfield Hospital, Haematology Mid and South Essex University Hospitals Group

Chelmsford, Essex, United Kingdom, CM1 7ET

Actively Recruiting

22

United Lincolnshire Teaching Hospital NHS Trust

Lincoln, Lincolnshire, United Kingdom, LN2 5QY

Actively Recruiting

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Research Team

A

Astghik Voskanyan, MD

D

Davit Melkonyan

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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