Actively Recruiting
Bleeding Patterns in Sequential and Continuous Progesterone Supplementation in Adolescents With Turner Syndrome
Led by Children's Mercy Hospital Kansas City · Updated on 2025-09-04
40
Participants Needed
1
Research Sites
52 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This is a single-site open label non-randomized study comparing effects of sequential versus continuous use of progesterone supplementation amongst Turner Syndrome (TS) patients with primary ovarian insufficiency (POI) prescribed hormone replacement therapy (HRT).
CONDITIONS
Official Title
Bleeding Patterns in Sequential and Continuous Progesterone Supplementation in Adolescents With Turner Syndrome
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Diagnosis of Turner Syndrome and Primary Ovarian Insufficiency
- Prescribed adult dosing of transdermal or oral estradiol for estrogen replacement therapy (50-200 µg/day transdermal or 2-4 mg/day oral)
- Have achieved menarche
You will not qualify if you...
- Disclosure of sexual activity and desire for contraception
- Having a levonorgestrel-releasing intrauterine device or etonogestrel arm implant
- Having received depot medroxyprogesterone within one year prior to study recruitment
- Non-English or non-Spanish speaking
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Children's Mercy Hospital
Kansas City, Missouri, United States, 64108
Actively Recruiting
Research Team
A
Allie Ranallo
CONTACT
A
Andrea Manlove
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NON_RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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