Actively Recruiting
Efficacy of Intranasal Sphenopalatine Ganglion Block by Lidocaine Spray for Partial Turbinectomy Surgeries
Led by Ain Shams University · Updated on 2026-04-30
50
Participants Needed
1
Research Sites
5 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This research aims to evaluate the effectiveness of blocking the sphenopalatine ganglion (SPG) using intranasal lidocaine spray during partial turbinectomy surgeries. These surgeries typically address chronic nasal congestion and related symptoms such as headaches, breathing difficulties, and sleep disorders including obstructive sleep apnea. The study focuses on improving pain management, reducing opioid use, and enhancing recovery and patient satisfaction, especially in patients who may have higher risks due to age, obesity, or sleep apnea. Participants will be randomly assigned to one of two groups. Both groups receive standardized general anesthesia including fentanyl, propofol, rocuronium, sevoflurane, morphine, paracetamol, and ketorolac. The experimental group will also receive intranasal lidocaine 10% spray applied bilaterally targeting the sphenopalatine fossa, with a total dose not exceeding 3 mg/kg actual body weight. Rescue analgesia protocols and postoperative pain management are the same for both groups. During the study, participants will be monitored for intraoperative fentanyl doses, heart rate, blood pressure, and postoperative pain using visual analog scores. Additional assessments include total postoperative pethidine use, time to extubation, and recovery scores. The trial includes a follow-up period up to 12 hours postoperatively to measure pain and recovery outcomes. Overall participation duration depends on surgical and immediate postoperative recovery timelines.
CONDITIONS
Brief Title
Blocking Sphenopalatine Ganglion by Intranasal Lidocaine Spray in Partial Turbinectomy Surgeries
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Undergoing elective partial turbinectomy surgery
- Age 18 years or older
You will not qualify if you...
- Patient refusal
- Kidney or liver impairment
- Pregnant or breast-feeding women
- Allergy to any of the drugs used in the study
- Operating room time more than 90 minutes (from anesthesia induction to end of surgery, excluding extubation)
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Day of surgery
Participants undergo partial turbinectomy surgery with general anesthesia. They receive either balanced anesthesia alone or balanced anesthesia plus intranasal lidocaine spray targeting the sphenopalatine ganglion to manage pain and improve surgical outcomes.
1 surgical visit (in-person)
Duration - Up to 48 hours post surgery
Participants are monitored for pain, recovery, and adverse effects with scheduled postoperative analgesia and assessments.
Multiple visits during hospital stay up to 48 hours
Trial Site Locations
Total: 1 location
1
Ain shams university hospitals
Cairo, Egypt
Actively Recruiting
Research Team
A
Abdallah soudi, M.D.
How is the study designed?
Study Type
INTERVENTIONAL
Masking
TRIPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
PREVENTION
Number of Arms
2
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