Actively Recruiting

Age: 0 - 18Years
All Genders
NCT07029230

Blood Based Assessment of sST2, Taken During and After Surgery, for Pediatric Patients With Heart Defects to Predict Heart Failure.

Led by Martin Schweiger · Updated on 2025-11-17

225

Participants Needed

1

Research Sites

177 weeks

Total Duration

On this page

Sponsors

M

Martin Schweiger

Lead Sponsor

U

University Children's Hospital, Zurich

Collaborating Sponsor

AI-Summary

What this Trial Is About

Patients younger than 18 scheduled for congenital heart surgery will be assessed during and post-operatively as well as at the first follow-up after 9-12 month for the novel biomarker sST2. We will assess the marker independently and in evaluation with other blood biomarkers to evaluate sings of heart failure. Compared to established biomarkers, sST2 promises thereby to be less variable to factors like age or acute kidney injury, rendering it potentially more reliable in the field of congenital cardiac surgery.

CONDITIONS

Official Title

Blood Based Assessment of sST2, Taken During and After Surgery, for Pediatric Patients With Heart Defects to Predict Heart Failure.

Who Can Participate

Age: 0 - 18Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Consent given for cardiopulmonary bypass surgery for a cardiac reason
  • Child and/or representative can understand and sign written consent in German
Not Eligible

You will not qualify if you...

  • Known genetic life-limiting conditions
  • Syndromes requiring or likely requiring surgery on more than one organ
  • Body weight less than 2.5 kilograms at time of surgery
  • Currently enrolled in an interventional study protocol

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

University Children's Hospital Zurirch

Zurich, Canton of Zurich, Switzerland, 8008

Actively Recruiting

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Research Team

M

Martin Schweiger, Prof, MD, MBA

CONTACT

C

Clemens Haselmann, MD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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