Actively Recruiting
Blood-based Biomarkers for Diagnosis of Alzheimer's
Led by Helse Stavanger HF · Updated on 2023-09-28
300
Participants Needed
1
Research Sites
343 weeks
Total Duration
On this page
Sponsors
H
Helse Stavanger HF
Lead Sponsor
S
Sahlgrenska University Hospital
Collaborating Sponsor
AI-Summary
What this Trial Is About
Alzheimer's disease (AD) may currently be diagnosed using molecular biomarkers in cerebrospinal fluid (CSF) and/or positron emission tomography (PET). These diagnostic procedures are highly accurate, but the high cost and low availability hamper their feasibility. Recently, ultrasensitive blood tests predicting Alzheimer pathologies in the brain have been developed. These tests have a reliable ability to differentiate AD from other neurodegenerative disorders and identify AD across the clinical continuum with high sensitivity and specificity in research cohorts with a high prevalence of AD. This project will assess the predictive value of these tests in a general practice population. The hypothesis is that the actual blood panel will have high positive predictive value for a diagnosis of Alzheimer's disease in the primary health care setting.
CONDITIONS
Official Title
Blood-based Biomarkers for Diagnosis of Alzheimer's
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Participants suspected by their GP to have possible dementia based on history, clinical examination, or cognitive screening
You will not qualify if you...
- Lack of capacity for consent as judged by the GP
- Severe psychiatric disease, use of medication, or physical disease that may affect participation or significantly contribute to cognitive impairment
- Patients unwilling to be referred to the memory outpatient clinic
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Stavanger University Hospital
Stavanger, Norway, 4068
Actively Recruiting
Research Team
S
Svein R Kjosavik, MD PhD
CONTACT
A
Anita L. Sunde, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
QUADRUPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
DIAGNOSTIC
Number of Arms
2
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