Actively Recruiting
Blood Based Risk Evaluation With AI for Targeted Primary Health Care in Early Lung Cancer Detection
Led by Vejle Hospital · Updated on 2026-05-06
1000
Participants Needed
2
Research Sites
417 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The study is a prospective, non-randomized feasibility study evaluating blood sample and machine learning-based risk stratification for lung cancer in patients with COPD (chronic obstructive pulmonary disease). Patients with COPD will be recruited in general practice, where they will have a blood sample drawn. All data will be analyzed by the machine learning model, and patients with increased risk of lung cancer will be referred for a low-dose CT scan of the chest. The primary objective of the study is to evaluate the feasibility of AI and DNA methylation-based risk stratification for lung cancer in patients with COPD in a primary care setting. The secondary objectives are to evaluate the safety of the risk stratification approach, the potential effects on quality of life and wellbeing, to gain insight into the patient and physician perspectives, and to estimate the health economic consequences.
CONDITIONS
Official Title
Blood Based Risk Evaluation With AI for Targeted Primary Health Care in Early Lung Cancer Detection
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Diagnosed with COPD
- Age 50 years or older
- Former or current smoker
- Speaks and understands Danish
- Able to give informed consent to participate
You will not qualify if you...
- Had a chest CT scan within the past 6 months
- Received active cancer treatment within the past year (except for non-melanoma skin cancer and carcinoma in situ cervicis uteri)
- Diagnosed with cancer within the past year (except for non-melanoma skin cancer and carcinoma in situ cervicis uteri)
- Has symptoms suspicious of cancer (except non-melanoma skin cancer and carcinoma in situ cervicis uteri)
- Has a condition that prevents diagnostic workup or treatment of lung cancer
- Does not have Eboks (electronic communication with Danish authorities)
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 2 locations
1
Lillebaelt Hospital Vejle, University Hospital of Southern Denmark
Vejle, Denmark, 7100
Actively Recruiting
2
General practices, Vejle area
Vejle, Denmark
Actively Recruiting
Research Team
S
Sara Witting Christensen WC Wen, MD, PhD
CONTACT
L
Lene Horsted, Study nurse
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
OTHER
Number of Arms
1
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