Actively Recruiting
Blood Changes After Exercise in Restless Legs Syndrome
Led by Stanford University · Updated on 2024-11-27
30
Participants Needed
1
Research Sites
110 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The goal of this clinical trial is to learn how exercise changes molecules in the blood in people with restless legs syndrome (RLS) to better understand the cause(s) of RLS. The main questions the investigators aim to answer are: How does long-term exercise change proteins in the blood? How does a single exercise session change proteins in the blood? The investigators will compare long-term exercise to no exercise to see if the changes in proteins are specific to exercise. Participants will complete an exercise test and provide blood samples before and after the exercise test. Participants will be randomized (like the flip of a coin) in to either the exercise or no-exercise group for 12 weeks and then complete the exercise test and blood samples again at the end.
CONDITIONS
Official Title
Blood Changes After Exercise in Restless Legs Syndrome
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 18 years or older
- Diagnosis of restless legs syndrome (RLS)
- Moderate-to-severe RLS with IRLS score greater than 15
- Currently untreated for RLS
- Not regularly active (less than 30 minutes of activity on more than 2 days per week in the past 6 months)
- Able to walk without assistance (no cane, walker, or wheelchair use)
- Willing to complete outcome measures and the exercise program
You will not qualify if you...
- Conditions that mimic or cause secondary RLS (such as iron deficiency anemia, radiculopathy, peripheral edema, peripheral neuropathy, diabetes)
- Moderate or high risk for strenuous or maximal exercise
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Stanford University
Stanford, California, United States, 94304
Actively Recruiting
Research Team
K
Katie Cederberg, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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