Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT06434272

Blood Flow Restriction Exercise in Patients With an Achilles Tendon Rupture

Led by University of Aarhus · Updated on 2025-04-17

218

Participants Needed

1

Research Sites

153 weeks

Total Duration

On this page

Sponsors

U

University of Aarhus

Lead Sponsor

A

Aarhus University Hospital

Collaborating Sponsor

AI-Summary

What this Trial Is About

The goal of this clinical trial is to gain insights into the effects of Blood Flow Restriction Exercise (BFRE) in patients with an acute Achilles tendon Rupture. The main questions it aims to answer are: Is BFRE an effective adjunct to usual care when compared with only usual care? When is the optimal timing for initiating BFRE: In the early treatment stage or at the later stage after hospital treatment? Participants will receive an intervention comprising 12 weeks of BFRE as an adjunct to usual care. * Either in the initial 1-12 weeks after Achilles tendon rupture, or * In the following 13-24 weeks after Achilles tendon rupture Researchers will compare the two groups at 13 weeks (3 months) to compare BFRE to usual care, and at 25 weeks (6 months) to compare the two time points for initiating BFRE (early vs. late).

CONDITIONS

Official Title

Blood Flow Restriction Exercise in Patients With an Achilles Tendon Rupture

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Aged 18 years or older
  • Started initial treatment within 72 hours of Achilles tendon rupture
  • Understand written and spoken Danish
Not Eligible

You will not qualify if you...

  • Bilateral Achilles tendon rupture
  • Previous Achilles tendon rupture in either leg
  • Decreased lower extremity function from conditions other than Achilles tendon rupture
  • Treated with fluoroquinolones within the last six months
  • Treated with corticosteroid injections near the Achilles tendon within the last six months
  • Diabetes
  • Previous diagnosed thrombosis
  • Known atherosclerosis in peripheral arteries of the lower limb
  • Other exclusion reasons (cognitive deficits, inability to consent, requiring cast treatment due to low compliance)

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

1
2
3
+1

Trial Site Locations

Total: 1 location

1

Aarhus University Hospital

Aarhus N, Denmark, 8200

Actively Recruiting

Loading map...

Research Team

A

Andreas Bentzen, MHSc

CONTACT

I

Inger Mechlenburg, DMSc

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

Not the Right Trial for You?

Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.

Already have an account? Log in here