Actively Recruiting
Does Blood Flow Restriction Training Improve Quadriceps Function After Arthroscopic Knee Surgery? A Randomized Clinical Trial
Led by The University of Texas Health Science Center, Houston · Updated on 2022-05-04
150
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
Sponsors
T
The University of Texas Health Science Center, Houston
Lead Sponsor
M
Memorial Hermann Hospital
Collaborating Sponsor
AI-Summary
What this Trial Is About
Researchers are evaluating whether adding blood flow restriction (BFR) training to physical therapy (PT) helps improve quadriceps muscle function after ACL reconstruction surgery. The study compares PT with BFR versus PT alone in patients needing extended limited weight bearing. The goal is to see if BFR can reduce muscle loss, increase strength, and improve early recovery outcomes following surgery. Participants receive physical therapy consisting of two or three 90-minute sessions per week for six weeks, totaling at least 18 visits. In the experimental group, BFR exercises are done at 30% of the one-repetition maximum with a cuff placed around the upper thigh, inflated to about 80% of limb occlusion pressure. The control group receives the same PT schedule without BFR. During the study, researchers will assess changes in quadriceps muscle size using ultrasound at multiple time points: start of PT, and 1, 2, and 5 months after. They will also measure muscle strength, range of motion, thigh circumference, and various functional performance tests over the same periods. Patient-reported outcomes on knee function, activity levels, fear of movement, and readiness to return to sport will be tracked. The study aims to understand how these treatments affect recovery after ACL surgery.
CONDITIONS
Brief Title
Does Blood Flow Restriction Training Improve Quadriceps Function After Arthroscopic Knee Surgery?
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Anterior cruciate ligament (ACL) reconstruction with concomitant meniscus or cartilage restoration procedures
- Adherence to modified weight bearing status before initiation of physical therapy
- Expected participation in recreational or competitive sports after release to full activities
You will not qualify if you...
- Unable to attend or participate in physical therapy
- Pregnancy
- Malignancy
- Fracture
- Peripheral vascular disease
- History of deep vein thrombosis (DVT)
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - 6 weeks
Participants undergo physical therapy consisting of two or three 90-minute sessions per week for 6 weeks, with or without blood flow restriction using a cuff inflated to 80% limb occlusion pressure during exercises.
18 physical therapy sessions over 6 weeks
Duration - Up to 5 months after start of physical therapy
Participants are assessed for changes in quadriceps function, range of motion, strength, thigh circumference, functional performance, activity levels, knee function, kinesiophobia, and physiological impact of returning to sport at multiple time points after physical therapy starts.
Assessments at start, 1 month, 2 months, and 5 months after physical therapy begins
Trial Site Locations
Total: 1 location
1
The University of Texas Health Science Center at Houston
Houston, Texas, United States, 77030
Actively Recruiting
Research Team
W
Walter R Lowe, MD
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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