Evaluating Blood Pressure Changes During Exercise and Aortic Stiffness in Adults with Cardiovascular-Kidney-Metabolic Syndrome

What this Trial Is About

The trial investigates the relationship between blood pressure response during exercise and aortic stiffness in adults with Cardiovascular-Kidney-Metabolic CKM syndrome, a condition involving cardiovascular disease, chronic kidney disease, and metabolic disorders like diabetes and obesity. The study aims to clarify whether blood pressure changes during routine exercise testing can serve as a simple, non-invasive marker to better assess cardiovascular risks in these patients. Participants are adults diagnosed with CKM syndrome who are referred for a routine exercise stress test by a cardiologist. During the single study visit, blood pressure will be measured immediately before and after the exercise test. Aortic stiffness will be assessed through transthoracic echocardiography by calculating the aortic stiffness index using measurements of the aortas size and blood pressure taken during the test. During the study visit, data on demographics, body measurements, cardiovascular risk factors, medications, lifestyle, and clinical history will be collected. The main outcome measured is the association between the change in blood pressure before and after exercise and aortic stiffness. This observational study lasts for one visit, with no additional treatments or long-term follow-up involved.

Blood Pressure Response to Exercise and Aortic Stiffness in Patients With Cardiovascular-Kidney-Metabolic Syndrome