Actively Recruiting

Age: 1Year - 75Years
All Genders
Healthy Volunteers
NCT02192866

Blood Samples for the Study of Peanut, Tree Nut and Other Food Allergies

Led by University of Colorado, Denver · Updated on 2022-12-19

270

Participants Needed

1

Research Sites

878 weeks

Total Duration

On this page

Sponsors

U

University of Colorado, Denver

Lead Sponsor

N

National Institutes of Health (NIH)

Collaborating Sponsor

AI-Summary

What this Trial Is About

Food allergies are now a major problem. These experiments involve getting blood from people with food allergies and from people without food allergies. The blood collected will be used to answer questions and find information about peanut and other food allergies. Samples will come from: * People signed up by the investigators at the University of Colorado Denver * University of North Carolina, Massachusetts General Hospital, Children's Hospital of Colorado and the Immune Tolerance Network (Benaroya Research Institute) where people have been treated for peanut allergies * University of North Carolina, Massachusetts General Hospital, National Jewish Health and The Children's Hospital in Denver where people have taken part or will take part in clinically indicated oral food challenges. Blood and health histories from the University of North Carolina, Massachusetts General Hospital, National Jewish Health, The Children's Hospital and the Immune Tolerance Network will not have personal information linked. The specific aims of this experiment are: 1. Come up with a lab test that will predict how bad an allergic reaction will be to peanuts. 2. Find out what part of a peanut causes allergic reactions. 3. Come up with preventions that can block peanut allergies. 4. Find the strongest proteins in walnuts.

CONDITIONS

Official Title

Blood Samples for the Study of Peanut, Tree Nut and Other Food Allergies

Who Can Participate

Age: 1Year - 75Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients enrolled in controlled oral immunotherapy trials for peanut allergy with at least one oral challenge, aged 1-75 years
  • Patients undergoing clinically indicated food challenges for peanut allergy, aged 1-75 years
  • Patients with an excellent history of systemic reaction to peanuts, aged 6-75 years
  • Patients with an excellent history of systemic reaction to tree nuts or other foods, aged 6-75 years
  • Normal controls with no known food allergies, recent ingestion of peanuts without difficulty, aged 6-75 years
Not Eligible

You will not qualify if you...

  • Any known significant medical or psychiatric diagnosis
  • Use of an investigational drug within 30 days
  • Use of omalizumab (anti-IgE; Xolair) within 6 months

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

University of Colorado School of Medicine

Denver, Colorado, United States, 80045

Actively Recruiting

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Research Team

S

Stephen Dreskin, MD, PhD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

3

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