Study Collecting Blood Samples to Understand Peanut, Tree Nut, and Other Food Allergies in Children and Adults

What this Trial Is About

This research aims to understand peanut, tree nut, and other food allergies by studying blood samples from people with these allergies and from those without. The study collects blood and health history from participants treated for peanut allergies or undergoing oral food challenges at multiple institutions. The goal is to develop lab tests predicting allergic reaction severity, identify allergenic peanut components, find prevention methods, and explore strong walnut proteins. Blood samples, including serum, plasma, and cells, are collected from participants with specific food allergies and controls. Existing de-identified samples and cord blood are also used. The study involves no therapeutic treatments but focuses on drawing blood and processing samples for laboratory experiments investigating immune responses and allergic proteins. Participants provide a single blood sample and share health history. Researchers analyze these samples to identify traits linked to severe allergies through tests like basophil activation and IgE binding. Personal information is removed from many samples to protect privacy. The study includes participants aged 1 to 75 and continues until December 2030, with no direct interventions or treatments given during participation.

Blood Samples for the Study of Peanut, Tree Nut and Other Food Allergies