Study of Blood Transfusion Risks and Use of Cell Saver Device in Children Undergoing Scoliosis Spine Surgery

What this Trial Is About

Pediatric patients undergoing spine surgery to correct scoliosis face significant risks related to blood loss during the procedure. This research aims to identify factors before and during surgery that increase the chance of needing transfusions of donor red blood cells. The study also evaluates how using a device called Cell Saver, which recycles the patients own blood during surgery, may reduce the need for these transfusions. The study looks at a group of children under 18 who had posterior instrumented spinal fusion surgery for scoliosis between April 2023 and March 2026. Researchers retrospectively analyze these cases to find risk factors for donor blood transfusions and assess the impact of reinfusing blood collected by the Cell Saver device during surgery. The surgical correction is done under general anesthesia using standard techniques. Participants data from the start of surgery until three days after are reviewed to measure how many required donor red blood cell transfusions and how much blood was saved by the Cell Saver device. The primary outcome is the proportion of patients needing donor blood within this period. Secondary outcomes include the rate of blood conservation achieved during surgery and total transfusion volume. This observational study is led by Mehdi Trifa and is expected to complete by the end of 2026.

Blood Transfusion Risk Factors and Cell Saver Impact in Pediatric Scoliosis Surgery