Actively Recruiting

Age: 18Years +
FEMALE
NCT04743674

Blood and Urine HPVDNA as Minimally Invasive Biomarkers for Cervical Cancer Detection and Surveillance Following Treatment

Led by UNC Lineberger Comprehensive Cancer Center · Updated on 2026-05-12

30

Participants Needed

2

Research Sites

141 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The purpose of this study is to determine if ctHPVDNA (circulating tumor HPV DNA) can be used as a non-invasive biomarker for identification and treatment monitoring of cervical cancer by characterizing correlation between plasma ctHPVDNA, urine transrenal HPVDNA (TrHPVDNA) levels and presence of cervical cancer at diagnosis and following definitive intent management.

CONDITIONS

Official Title

Blood and Urine HPVDNA as Minimally Invasive Biomarkers for Cervical Cancer Detection and Surveillance Following Treatment

Who Can Participate

Age: 18Years +
FEMALE

Eligibility Criteria

Eligible

You may qualify if you...

  • 18 years of age or older on day of signing informed consent
  • New diagnosis of cervical cancer
  • Willing and able to comply with study procedures based on investigator judgment
Not Eligible

You will not qualify if you...

  • Women who are pregnant

AI-Screening

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Trial Site Locations

Total: 2 locations

1

Melissa Knutsen

Chapel Hill, North Carolina, United States, 27599

Actively Recruiting

2

Kamuzu Central Hospital

Lilongwe, Malawi

Not Yet Recruiting

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Research Team

M

Melissa E Knutsen

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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