Urologic diseases in america project: benign prostatic hyperplasia.
John T Wei, Elizabeth Calhoun, Steven J Jacobsen
https://pubmed.ncbi.nlm.nih.gov/18405761/Actively Recruiting
Led by Chinese University of Hong Kong · Updated on 2025-08-11
10
Participants Needed
1
Research Sites
12 weeks
Total Duration
This research aims to evaluate the outcomes of using a blue diode laser vaporization procedure to treat benign prostatic hyperplasia BPH in men aged 50 and older. The study follows a single group of participants over one year to observe how this 450nm blue laser treatment affects symptoms and prostate function. Researchers are collecting detailed data to understand the clinical progress and safety of this approach under medical supervision. Participants will receive the blue diode laser vaporization treatment performed under spinal or general anesthesia using a 200W blue light laser. Follow-up visits are scheduled at 3 months, 6 months, and 12 months after the operation to monitor recovery and treatment effects. During these visits, various tests and questionnaires will be repeated to assess prostate size, urinary flow, symptoms, and quality of life. Throughout the study, participants will undergo blood and urine tests, ultrasound scans to measure prostate volume, and uroflowmetry to check urine flow. The International Prostate Symptom Score IPSS and other questionnaires will be used to evaluate symptoms and quality of life. Researchers will also monitor any adverse events, unplanned hospital admissions, and changes in erectile and ejaculatory function. The total time commitment for each participant is one year from treatment to final follow-up.
CONDITIONS
Blue Diode Laser Vaporization for BPH
K
Ka Fung Peter CHIU, MBChB PhD
K
Ka Fung CHIU
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Chinese University of Hong Kong
Lead Sponsor
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Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
Duration - Peri-operative period
Participants undergo blue diode laser vaporization of the prostate under spinal or general anesthesia, followed by immediate recovery and monitoring for peri-operative outcomes such as operation time, catheter use, and hospital stay.
1 surgical procedure and immediate post-operative monitoring
Duration - 12 months
Participants are followed up to assess urinary symptoms, urodynamic changes, quality of life, and adverse events after surgery. Blood tests, urine tests, ultrasound, uroflowmetry, and questionnaires are completed to monitor clinical progress.
Visits at 1 month, 3 months, 6 months, and 12 months after surgery
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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https://pubmed.ncbi.nlm.nih.gov/22914880/Chinese University of Hong Kong
Lead Sponsor