The prevalence of lower urinary tract symptoms in a Chinese population, and the correlation with uroflowmetry and disease perception.
Chi-Hang Yee, Joseph K M Li, Hon-Chung Lam...
https://pubmed.ncbi.nlm.nih.gov/24136186Actively Recruiting
Phase Not Applicable
Age: 50Years +
MALE
ID07115147
Blue Diode Laser Vaporization for Benign Prostatic Hyperplasia (BPH) in Men Aged 50 and Older
Led by Chinese University of Hong Kong · Updated on 2025-08-11
10
Participants Needed
1
Research Sites
12 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This research aims to evaluate the outcomes of using a blue diode laser vaporization procedure to treat benign prostatic hyperplasia (BPH) in men aged 50 and older. The study follows a single group of participants over one year to observe how this 450nm blue laser treatment affects symptoms and prostate function. Researchers are collecting detailed data to understand the clinical progress and safety of this approach under medical supervision. Participants will receive the blue diode laser vaporization treatment performed under spinal or general anesthesia using a 200W blue light laser. Follow-up visits are scheduled at 3 months, 6 months, and 12 months after the operation to monitor recovery and treatment effects. During these visits, various tests and questionnaires will be repeated to assess prostate size, urinary flow, symptoms, and quality of life. Throughout the study, participants will undergo blood and urine tests, ultrasound scans to measure prostate volume, and uroflowmetry to check urine flow. The International Prostate Symptom Score (IPSS) and other questionnaires will be used to evaluate symptoms and quality of life. Researchers will also monitor any adverse events, unplanned hospital admissions, and changes in erectile and ejaculatory function. The total time commitment for each participant is one year from treatment to final follow-up.
CONDITIONS
Brief Title
Blue Diode Laser Vaporization for BPH
Who Can Participate
Age: 50Years +
MALE
Eligibility Criteria
You may qualify if you...
- Male aged 50 years or older
- Symptomatic benign prostatic hyperplasia (BPH)
You will not qualify if you...
- Need for additional procedures such as cystolithotripsy or orchidectomy
- Known prostate cancer
- History of transurethral resection of the prostate (TURP)
- Known urethral stricture, bladder stone, or hypercontractile bladder
- Known neurological diseases affecting bladder function (e.g. Parkinsonism, stroke)
- Contraindications to TURP such as unfit for general or spinal anesthesia, active urinary tract infection, inability to assume lithotomy position, uncorrectable blood clotting issues, or use of antiplatelet/anticoagulant medications that cannot be stopped
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
1
2
3
Your Study Journey
Screening
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
Surgery and Immediate Post-operative Care
Duration - Peri-operative period
Participants undergo blue diode laser vaporization of the prostate under spinal or general anesthesia, followed by immediate recovery and monitoring for peri-operative outcomes such as operation time, catheter use, and hospital stay.
1 surgical procedure and immediate post-operative monitoring
Post-operative Follow-up
Duration - 12 months
Participants are followed up to assess urinary symptoms, urodynamic changes, quality of life, and adverse events after surgery. Blood tests, urine tests, ultrasound, uroflowmetry, and questionnaires are completed to monitor clinical progress.
Visits at 1 month, 3 months, 6 months, and 12 months after surgery
Trial Site Locations
Total: 1 location
1
Prince of Wales Hospital, Chinese University of Hong Kong
Hong Kong, Hong Kong
Actively Recruiting
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Research Team
K
Ka Fung Peter CHIU, MBChB PhD
K
Ka Fung CHIU
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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Published Research Related To This Trial
Ambulatory care program for patients presenting with acute urinary retention secondary to benign prostatic hyperplasia.
Jeremy Yuen Chun Teoh, Chi Fai Kan, Bess Tsui...
https://pubmed.ncbi.nlm.nih.gov/22914880Urologic diseases in america project: benign prostatic hyperplasia.
John T Wei, Elizabeth Calhoun, Steven J Jacobsen
https://pubmed.ncbi.nlm.nih.gov/18405761Photoselective vaporization with the green light laser vs transurethral resection of the prostate for treating benign prostate hyperplasia: a systematic review and meta-analysis.
Jingfei Teng, Dongxu Zhang, Yao Li...
https://pubmed.ncbi.nlm.nih.gov/23145474