Actively Recruiting
A Phase 3, Randomized, Double-blind Study to Evaluate the Efficacy and Safety of Bomedemstat Versus Hydroxyurea in Cytoreductive Therapy Naffve Essential Thrombocythemia
Led by Merck Sharp & Dohme LLC · Updated on 2026-06-08
300
Participants Needed
171
Research Sites
25 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are evaluating the efficacy and safety of bomedemstat compared with hydroxyurea in adults diagnosed with essential thrombocythemia (ET) who have not previously received cytoreductive therapy but require it. The main goal is to see if bomedemstat can provide a better durable clinicohematologic response (DCHR) than hydroxyurea. This Phase 3, randomized, double-blind trial aims to improve treatment options for people with ET by comparing these two therapies. Participants will be randomly assigned to receive either active bomedemstat with a placebo for hydroxyurea or active hydroxyurea with a placebo for bomedemstat. Both treatments are given as oral capsules daily for up to 52 weeks, with doses adjusted to safely reduce platelet counts within a target range. After completing the initial treatment period, eligible participants may continue treatment in an extended phase. Placebos will be stopped and unblinding will occur once all participants finish or discontinue the 52-week therapy. During the study, participants will have regular assessments to monitor blood counts, symptom changes using specific fatigue and symptom questionnaires, and the occurrence of thrombotic or hemorrhagic events. Researchers will evaluate durable hematologic remission and disease progression up to Week 52. Safety will be closely followed through adverse event tracking. The total study participation includes the initial 52-week treatment and possible extension, with detailed monitoring throughout to assess treatment effects and safety.
CONDITIONS
Brief Title
Bomedemstat vs Hydroxyurea for Essential Thrombocythemia (MK-3543-007)
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adults aged 18 years or older
- Diagnosis of Essential Thrombocythemia (ET) based on World Health Organization criteria
- Indication for cytoreductive therapy regardless of age or risk status
- Bone marrow fibrosis score of Grade 0 or Grade 1 as assessed centrally
- No prior cytoreductive treatment for ET
- Well-controlled HIV infection on antiretroviral therapy
- Hepatitis B surface antigen positive participants eligible if on antiviral therapy for at least 4 weeks with undetectable viral load
- Participants with history of Hepatitis C virus infection eligible if viral load is undetectable
You will not qualify if you...
- History of gastrointestinal illness or impairment that might interfere with drug absorption
- History of any malignancy unless potentially curative treatment completed with no evidence of cancer for 2 years
- HIV-infected participants with history of Kaposi's sarcoma or Multicentric Castleman's Disease
- Active infection requiring systemic therapy
- Major surgery within 4 weeks prior to first dose or not recovered from side effects of major surgery done more than 4 weeks before first dose
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Up to approximately 52 weeks
Participants receive daily oral capsules of either bomedemstat or hydroxyurea (with matching placebos) for cytoreductive therapy. Dosage is adjusted to safely lower platelet counts to the target range.
Regular visits for dosage adjustment and monitoring during treatment
Trial Site Locations
Total: 171 locations
1
Palo Verde Cancer Specialists ( Site 0052)
Glendale, Arizona, United States, 85304
Actively Recruiting
2
Los Angeles Cancer Network ( Site 0025)
Glendale, California, United States, 91206
Actively Recruiting
3
Stanford Cancer Center ( Site 0024)
Palo Alto, California, United States, 94304
Actively Recruiting
4
Exempla Lutheran Medical Center ( Site 0014)
Golden, Colorado, United States, 80401
Actively Recruiting
5
Yale University School of Medicine ( Site 0051)
New Haven, Connecticut, United States, 06510
Actively Recruiting
6
Parkview Research Center at Parkview Regional Medical Center ( Site 0006)
Fort Wayne, Indiana, United States, 46845
Completed
7
University of Michigan ( Site 0003)
Ann Arbor, Michigan, United States, 48109
Actively Recruiting
8
Optum Care Cancer Center ( Site 0053)
Las Vegas, Nevada, United States, 89102
Actively Recruiting
9
Levine Cancer Institute ( Site 0009)
Charlotte, North Carolina, United States, 28204
Actively Recruiting
10
Duke University Health System (DUHS) ( Site 0012)
Durham, North Carolina, United States, 27710
Actively Recruiting
11
Wake Forest Baptist Health-Internal Medicine, Section on Hematology & Oncology ( Site 0013)
Winston-Salem, North Carolina, United States, 27157
Actively Recruiting
12
The Ohio State University Wexner Medical Center ( Site 0028)
Columbus, Ohio, United States, 43210
Actively Recruiting
13
Oncology Associates of Oregon, P.C.(Willamette Valley Cancer Institute) (WVCI) ( Site 8005)
Eugene, Oregon, United States, 97401
Actively Recruiting
14
Oregon Health & Science University ( Site 0018)
Portland, Oregon, United States, 97239
Actively Recruiting
15
TriStar Bone Marrow ( Site 7000)
Nashville, Tennessee, United States, 37203
Actively Recruiting
16
Texas Oncology - West Texas ( Site 8003)
Amarillo, Texas, United States, 79124
Actively Recruiting
17
Texas Oncology - DFW ( Site 8006)
Dallas, Texas, United States, 75246
Actively Recruiting
18
University of Texas MD Anderson Cancer Center ( Site 0026)
Houston, Texas, United States, 77030
Actively Recruiting
19
University of Texas Health Science Center at San Antonio ( Site 0021)
San Antonio, Texas, United States, 78229
Actively Recruiting
20
Texas Oncology - Gulf Coast ( Site 8008)
Webster, Texas, United States, 77598
Actively Recruiting
21
University of Virginia ( Site 0020)
Charlottesville, Virginia, United States, 22908
Actively Recruiting
22
VCU Health Adult Outpatient Pavillion ( Site 0008)
Richmond, Virginia, United States, 23219
Actively Recruiting
23
Hospital Universitario Austral ( Site 0101)
Pilar, Buenos Aires, Argentina, B1629AHJ
Actively Recruiting
24
Hospital Italiano de Buenos Aires ( Site 0102)
ABB, Buenos Aires F.D., Argentina, C1199ABB
Actively Recruiting
25
C.I.C.E. 9 de Julio ( Site 0104)
San Miguel de Tucumán, Tucumán Province, Argentina, T4000IKO
Actively Recruiting
26
Clínica de Nefrología, Urología y Enfermedades Cardiovasculares ( Site 0105)
Santa Fe, Argentina, 3000
Actively Recruiting
27
Westmead Hospital ( Site 0201)
Westmead, New South Wales, Australia, 2115
Completed
28
Royal Adelaide Hospital-Haematology Clinical Trials Unit ( Site 0203)
Adelaide, South Australia, Australia, 5000
Actively Recruiting
29
Monash Health-Haematology Research ( Site 0202)
Clayton, Victoria, Australia, 3168
Actively Recruiting
30
Austin Health-Cancer Clinical Trials Centre ( Site 0206)
Heidelberg, Victoria, Australia, 3084
Actively Recruiting
31
Royal Perth Hospital-Haematology ( Site 0204)
Perth, Western Australia, Australia, 6000
Actively Recruiting
32
Ordensklinikum Linz GmbH Elisabethinen ( Site 0562)
Linz, Upper Austria, Austria, 4020
Actively Recruiting
33
Arthur J.E. Child Comprehensive Cancer Centre ( Site 0038)
Calgary, Alberta, Canada, T2N 5G2
Actively Recruiting
34
Centre Intégré de Santé et de Services Sociaux de la Montérégie-Centre ( Site 0037)
Greenfield Park, Quebec, Canada, J4V 2H1
Actively Recruiting
35
Biocenter ( Site 0149)
Concepción, Biobio, Chile, 4070196
Active, Not Recruiting
36
IC La Serena Research ( Site 0150)
La Serena, Coquimbo Region, Chile, 1720430
Active, Not Recruiting
37
FALP-UIDO ( Site 0148)
Santiago, Region M. de Santiago, Chile, 7500921
Active, Not Recruiting
38
Clínica Inmunocel ( Site 0147)
Santiago, Region M. de Santiago, Chile, 7580206
Active, Not Recruiting
39
Clínica Alemana de Santiago ( Site 0143)
Santiago, Region M. de Santiago, Chile, 7650568
Active, Not Recruiting
40
Bradfordhill-Clinical Area ( Site 0142)
Santiago, Region M. de Santiago, Chile, 8420383
Active, Not Recruiting
41
The First Afflilated Hospital of Bengbu Medical College ( Site 0651)
Bengbu, Anhui, China, 233004
Actively Recruiting
42
Anhui Provincial Hospital ( Site 0657)
Hefei, Anhui, China, 230001
Actively Recruiting
43
Peking University Third Hospital-Hematology ( Site 0659)
Beijing, Beijing Municipality, China, 100191
Actively Recruiting
44
Chinese Academy of medical science, Peking Union Medical College Hospital(Dongdan) ( Site 0675)
Beijing, Beijing Municipality, China, 100730
Actively Recruiting
45
Chongqing University Cancer Hospital ( Site 0666)
Chongqing, Chongqing Municipality, China, 400030
Actively Recruiting
46
The Second Affiliated Hospital of Fujian Medical University ( Site 0671)
Quanzhou, Fujian, China, 362000
Actively Recruiting
47
The First Affiliated hospital of Xiamen University ( Site 0658)
Xiamen, Fujian, China, 361003
Actively Recruiting
48
Sun Yat-sen Memorial Hospital, Sun Yat-sen University-hematology department ( Site 0668)
Guangzhou, Guangdong, China, 510120
Actively Recruiting
49
Southern Medical University Nanfang Hospital-Department of Hematopathology ( Site 0655)
Guangzhou, Guangdong, China, 510515
Actively Recruiting
50
The Second Afilliated Hospital of Hebei Medical University ( Site 0650)
Shijiazhuang, Hebei, China, 050000
Actively Recruiting
51
The First Hospital of Hebei Medical University ( Site 0649)
Shijiazhuang, Hebei, China, 050031
Actively Recruiting
52
Henan Cancer Hospital-hematology department ( Site 0644)
Zhengzhou, Henan, China, 450008
Actively Recruiting
53
Union Hospital Tongji Medical College Huazhong University of Science and Technology ( Site 0642)
Wuhan, Hubei, China, 430022
Active, Not Recruiting
54
The First Affiliated Hospital of Soochow University ( Site 0676)
Suzhou, Jiangsu, China, 215006
Actively Recruiting
55
The First affiliated hospital of Nanchang University (Xianghu campus) ( Site 0645)
Nanchang, Jiangxi, China, 330209
Actively Recruiting
56
The First Hospital of Jilin University-Hematology ( Site 0672)
Changchun, Jilin, China, 130021
Actively Recruiting
57
Shaanxi provincial people's hospital ( Site 0652)
Xi'an, Shaanxi, China, 710068
Actively Recruiting
58
Jinan Central Hospital ( Site 0667)
Jinan, Shandong, China, 250013
Actively Recruiting
59
Zhongshan Hospital,Fudan University-Hematology ( Site 0674)
Shanghai, Shanghai Municipality, China, 200032
Actively Recruiting
60
Huashan Hospital, Fudan University ( Site 0669)
Shanghai, Shanghai Municipality, China, 200040
Actively Recruiting
61
West China Hospital, Sichuan University ( Site 0661)
Chengdu, Sichuan, China, 610041
Actively Recruiting
62
Institute of hematology&blood disease hospital-Hematology ( Site 0641)
Tianjin, Tianjin Municipality, China, 301636
Actively Recruiting
63
The first Affiliated Hospital, Zhejiang University School of Medicine ( Site 0646)
Hangzhou, Zhejiang, China, 310000
Actively Recruiting
64
Zhejiang University School of Medicine-The Fourth Affiliated Hospital ( Site 0662)
Yiwu, Zhejiang, China, 322000
Actively Recruiting
65
Fundacion Colombiana de Cancerología Clinica Vida ( Site 0164)
Medellín, Antioquia, Colombia, 050030
Active, Not Recruiting
66
Los Cobos Medical Center ( Site 0165)
Bogotá, Bogota D.C., Colombia, 110121
Active, Not Recruiting
67
IMAT S.A.S ( Site 0162)
Montería, Departamento de Córdoba, Colombia, 230002
Active, Not Recruiting
68
Rigshospitalet-Hematology - CTU ( Site 0321)
Copenhagen, Capital Region, Denmark, 2100
Actively Recruiting
69
Aarhus Universitetshospital, Skejby-Blodsygdomme ( Site 0324)
Aarhus, Central Jutland, Denmark, 8200
Actively Recruiting
70
Roskilde Sygehus-Department of Hematology ( Site 0323)
Roskilde, Region Sjælland, Denmark, 4000
Actively Recruiting
71
Odense Universitetshospital-Department of Hematology ( Site 0325)
Odense C, Region Syddanmark, Denmark, 5000
Actively Recruiting
72
Centre Hospitalier Universitaire de Nice - Hôpital l'Archet-Hematology ( Site 0349)
Nice, Alpes-Maritimes, France, 06202
Actively Recruiting
73
CHU Bordeaux Haut-Leveque-service de mèdecine interne et maladies infectieuses ( Site 0346)
Pessac, Aquitaine, France, 33600
Actively Recruiting
74
Hôpital de la Conception ( Site 0351)
Marseille, Bouches-du-Rhone, France, 13005
Actively Recruiting
75
Institut Universitaire du Cancer Toulouse - Oncopole - CHU de TOULOUSE ( Site 0352)
Toulouse, Haute-Garonne, France, 31059
Actively Recruiting
76
Centre Hospitalier Universitaire de Limoges - Hôpital Dupuytren ( Site 0344)
Limoges, Haute-Vienne, France, 87042
Completed
77
Centre Hospitalier Régional Universitaire de Tours - Hôpital-Hématologie et Thérapie Cellulaire ( Site 0342)
Tours, Indre-et-Loire, France, 37000
Actively Recruiting
78
Centre Hospitalier Universitaire de Nantes - L' Hopital l'hôtel-Dieu ( Site 0347)
Nantes, Pays de la Loire Region, France, 44093
Completed
79
centre hospitalier lyon sud ( Site 0343)
Pierre-Bénite, Rhone, France, 69310
Actively Recruiting
80
HENRI MONDOR HOSPITAL ( Site 0348)
Créteil, Val-de-Marne, France, 94010
Completed
81
Hopital Saint-Louis ( Site 0341)
Paris, France, 75010
Actively Recruiting
82
VK&K Studien GbR ( Site 0370)
Landshut, Bavaria, Germany, 84036
Active, Not Recruiting
83
Medizinische Hochschule Hannover ( Site 0371)
Hanover, Lower Saxony, Germany, 30625
Completed
84
Universitätsklinikum Aachen ( Site 0367)
Aachen, North Rhine-Westphalia, Germany, 52074
Active, Not Recruiting
85
Universitaetsklinikum Essen ( Site 0366)
Essen, North Rhine-Westphalia, Germany, 45147
Active, Not Recruiting
86
Universitätsmedizin Johannes Gutenberg Universität Mainz-3. Medizinische Klinik und Poliklinik ( Site 0365)
Mainz, Rhineland-Palatinate, Germany, 55131
Active, Not Recruiting
87
Universitätsklinikum Halle ( Site 0361)
Halle, Saxony-Anhalt, Germany, 06120
Active, Not Recruiting
88
Universitätsklinikum Jena-Klinik für Innere Medizin II, Abt. Hämatologie und Internistische Onkolog ( Site 0364)
Jena, Thuringia, Germany, 07747
Completed
89
Charité Universitaetsmedizin Berlin - Campus Mitte ( Site 0369)
Berlin, Germany, 13353
Completed
90
Queen Mary Hospital ( Site 0221)
Hksar, Hong Kong
Actively Recruiting
91
Szegedi Tudományegyetem Szent-Györgyi Albert Klinikai Központ-Belgyógyászati Klinika ( Site 0407)
Szeged, Csongrád megye, Hungary, 6725
Actively Recruiting
92
Petz Aladar Egyetemi Oktato Korhaz-Hematológia ( Site 0405)
Győr, Győr-Moson-Sopron, Hungary, 9024
Active, Not Recruiting
93
Somogy Vármegyei Kaposi Mór Oktató Kórház-Haematológiai osztály ( Site 0406)
Kaposvár, Somogy County, Hungary, 7400
Active, Not Recruiting
94
Szabolcs-Szatmár-Bereg Megyei Kórházak és Egyetemi Oktatókór-Haematológia osztály ( Site 0404)
Nyíregyháza, Szabolcs-Szatmár-Bereg, Hungary, 4400
Active, Not Recruiting
95
Debreceni Egyetem Klinikai Kozpont-Belgyógyászati Klinika (Haematologia) ( Site 0402)
Debrecen, Hungary, 4032
Active, Not Recruiting
96
Soroka Medical Center ( Site 0427)
Beersheba, Israel, 8410101
Actively Recruiting
97
Rambam Health Care Campus ( Site 0429)
Haifa, Israel, 3109601
Actively Recruiting
98
Carmel Hospital ( Site 0426)
Haifa, Israel, 3436212
Actively Recruiting
99
Hadassah Medical Center ( Site 0424)
Jerusalem, Israel, 9112001
Actively Recruiting
100
Galilee Medical Center ( Site 0431)
Nahariya, Israel, 2201202
Actively Recruiting
101
Rabin Medical Center ( Site 0425)
Petah Tikva, Israel, 4941492
Actively Recruiting
102
Sheba Medical Center ( Site 0428)
Ramat Gan, Israel, 5265601
Actively Recruiting
103
Sourasky Medical Center ( Site 0422)
Tel Aviv, Israel, 6423906
Actively Recruiting
104
Yitzhak Shamir Medical Center. ( Site 0421)
Ẕerifin, Israel, 7033001
Actively Recruiting
105
Azienda Ospedaliera Universitaria Careggi ( Site 0441)
Florence, Tuscany, Italy, 50134
Actively Recruiting
106
Azienda Ospedaliero-Universitaria SS. Antonio e Biagio e Cesare Arrigo ( Site 0443)
Alessandria, Italy, 15121
Actively Recruiting
107
IRCCS Azienda Ospedaliero-Universitaria di Bologna, Policlinico di Sant'Orsola ( Site 0446)
Bologna, Italy, 40138
Actively Recruiting
108
Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico ( Site 0447)
Milan, Italy, 20122
Active, Not Recruiting
109
Fondazione IRCCS Policlinico San Matteo-Oncology ( Site 0444)
Pavia, Italy, 27100
Completed
110
Fondazione Policlinico Universitario Agostino Gemelli IRCCS - Università Cattolica del Sacro Cuore ( Site 0445)
Roma, Italy, 00168
Actively Recruiting
111
Ospedale di Circolo e Fondazione Macchi Varese ( Site 0442)
Varese, Italy, 21100
Actively Recruiting
112
Fujita Health University Hospital ( Site 0613)
Toyoake, Aichi-ken, Japan, 470-1192
Active, Not Recruiting
113
Ehime University Hospital ( Site 0612)
Tōon, Ehime, Japan, 791-0295
Active, Not Recruiting
114
Hokkaido University Hospital ( Site 0601)
Sapporo, Hokkaido, Japan, 060-8648
Active, Not Recruiting
115
Kobe City Medical Center General Hospital ( Site 0603)
Kobe, Hyōgo, Japan, 650-0047
Completed
116
Kanazawa University Hospital ( Site 0614)
Kanazawa, Ishikawa-ken, Japan, 920-8641
Active, Not Recruiting
117
Mie University Hospital ( Site 0615)
Tsu, Mie-ken, Japan, 514-8507
Active, Not Recruiting
118
National Hospital Organization Sendai Medical Center ( Site 0617)
Sendai, Miyagi, Japan, 983-8520
Active, Not Recruiting
119
Kansai Medical University Hospital ( Site 0607)
Hirakata, Osaka, Japan, 573-1191
Active, Not Recruiting
120
Kindai University Hospital ( Site 0600)
Sakai, Osaka, Japan, 590-0197
Active, Not Recruiting
121
Juntendo University Hospital ( Site 0611)
Bunkyo-ku, Tokyo, Japan, 113-8431
Completed
122
University of Yamanashi Hospital ( Site 0606)
Chūō, Yamanashi, Japan, 409-3898
Active, Not Recruiting
123
Kyushu University Hospital ( Site 0605)
Fukuoka, Japan, 812-8582
Completed
124
Fukushima Medical University Hospital ( Site 0616)
Fukushima, Japan, 960-1295
Active, Not Recruiting
125
University of Miyazaki Hospital ( Site 0609)
Miyazaki, Japan, 889-1692
Active, Not Recruiting
126
Okayama University Hospital ( Site 0604)
Okayama, Japan, 700-8558
Active, Not Recruiting
127
Nippon Medical School Hospital ( Site 0608)
Tokyo, Japan, 113-8603
Active, Not Recruiting
128
Medivest Centro de Investigación Integral ( Site 0183)
Chihuahua City, Chihuahua, Mexico, 31203
Active, Not Recruiting
129
Higiea Oncologia ( Site 0184)
Mexico City, Mexico City, Mexico, 11819
Active, Not Recruiting
130
Centro de Investigacion Clinica de Oaxaca ( Site 0181)
Oaxaca City, Oaxaca, Mexico, 68020
Active, Not Recruiting
131
Samodzielny Publiczny Szpital Kliniczny nr 1 w Lublinie-Oddział Hematoonkologii, Transplantacji Szp ( Site 0463)
Lublin, Lublin Voivodeship, Poland, 20-081
Actively Recruiting
132
Pratia Onkologia Katowice ( Site 0461)
Katowice, Silesian Voivodeship, Poland, 40-519
Actively Recruiting
133
Swietokrzyskie Centrum Onkologii, Samodzielny Publiczny Zakl-Klinika Hematologii i Transplantacji S ( Site 0466)
Kielce, Świętokrzyskie Voivodeship, Poland, 25-734
Actively Recruiting
134
Hospital Germans Trias i Pujol-Instituto Catalán de Oncología de Badalona ( Site 0490)
Badalona, Barcelona, Spain, 08916
Actively Recruiting
135
Institut Català d'Oncologia - L'Hospitalet ( Site 0482)
L'Hospitalet de Llobregat, Barcelona, Spain, 08908
Actively Recruiting
136
Hospital Universitario Marqués de Valdecilla-Haematology ( Site 0486)
Santander, Cantabria, Spain, 39008
Active, Not Recruiting
137
HOSPITAL CLÍNIC DE BARCELONA ( Site 0481)
Barcelona, Catalonia, Spain, 08036
Actively Recruiting
138
Clinica Universidad de Navarra-Hematology Department ( Site 0485)
Madrid, Madrid, Comunidad de, Spain, 28027
Actively Recruiting
139
Hospital Universitario Ramón y Cajal-Hematology ( Site 0484)
Madrid, Madrid, Comunidad de, Spain, 28034
Actively Recruiting
140
Hospital Costa del Sol-Hematology Service ( Site 0493)
Marbella, Malaga, Spain, 29603
Completed
141
Hospital Universitari Vall d'Hebron-Departamento de Oncologia- VHIO ( Site 0489)
Barcelona, Spain, 08035
Actively Recruiting
142
Hospital Universitario 12 de Octubre ( Site 0494)
Madrid, Spain, 28041
Actively Recruiting
143
Hospital Universitario de Salamanca - Complejo Asistencial Universitario de Salamanca-Hematology ( Site 0488)
Salamanca, Spain, 37007
Completed
144
Skånes Universitetssjukhus Lund-Department of Hematology ( Site 0544)
Lund, Skåne County, Sweden, 22185
Actively Recruiting
145
Karolinska Universitetssjukhuset Huddinge ( Site 0541)
Huddinge, Stockholm County, Sweden, 141 86
Actively Recruiting
146
Akademiska sjukhuset ( Site 0545)
Uppsala, Uppsala County, Sweden, 751 85
Actively Recruiting
147
Sahlgrenska Universitetssjukhuset-Department of hematology and coagulation ( Site 0543)
Gothenburg, Västra Götaland County, Sweden, 413 45
Actively Recruiting
148
Universitetssjukhuset Örebro ( Site 0542)
Örebro, Örebro County, Sweden, 701 85
Actively Recruiting
149
Chang Gung Memorial Hospital- Chiayi ( Site 0242)
Chiayi City, Chiayi, Taiwan, 613
Active, Not Recruiting
150
National Cheng Kung University Hospital-Clinical Trial Center ( Site 0245)
Tainan, Taiwan, 704
Active, Not Recruiting
151
National Taiwan University Hospital ( Site 0241)
Taipei, Taiwan, 10002
Active, Not Recruiting
152
Chang Gung Medical Foundation-Linkou Branch ( Site 0243)
Taoyuan, Taiwan, 33305
Active, Not Recruiting
153
Ege Universitesi Hastanesi ( Site 0503)
Bornova, İzmir, Turkey (Türkiye), 35100
Actively Recruiting
154
Dr. Abdurrahman Yurtaslan Ankara Onkoloji Egitim ve Arastırma Hastanesi-Hemotology ( Site 0510)
Ankara, Turkey (Türkiye), 06200
Actively Recruiting
155
Hacettepe Universite Hastaneleri-Department of Hematology ( Site 0505)
Ankara, Turkey (Türkiye), 06230
Actively Recruiting
156
Ankara Bilkent Şehir Hastanesi-Medical Oncology ( Site 0502)
Ankara, Turkey (Türkiye), 06800
Actively Recruiting
157
Ankara UTF Cebeci Arastırma ve Uygulama Hastanesi ( Site 0511)
Ankara, Turkey (Türkiye), 6620
Actively Recruiting
158
Antalya Egitim ve Arastırma Hastanesi ( Site 0508)
Antalya, Turkey (Türkiye), 07100
Actively Recruiting
159
Trakya University Medical Faculty Hospital-Hematology ( Site 0501)
Edirne, Turkey (Türkiye), 22030
Actively Recruiting
160
Medipol Mega Universite Hastanesi ( Site 0504)
Istanbul, Turkey (Türkiye), 34214
Actively Recruiting
161
Kocaeli Üniversitesi-Hematology ( Site 0506)
Kocaeli, Turkey (Türkiye), 41380
Actively Recruiting
162
Ondokuz Mayıs Universitesi-hematology ( Site 0507)
Samsun, Turkey (Türkiye), 55139
Actively Recruiting
163
Glan Clwyd Hospital ( Site 0528)
Bodelwyddan, Denbighshire, United Kingdom, LL18 5UJ
Active, Not Recruiting
164
Gloucestershire Royal Hospital ( Site 0521)
Gloucester, Gloucestershire, United Kingdom, Gl1 3NN
Actively Recruiting
165
Lincoln County Hospital ( Site 0535)
Lincoln, Great Britain, United Kingdom, LN2 5QY
Actively Recruiting
166
Boston Pilgrim Hospital ( Site 0525)
Boston, Lincolnshire, United Kingdom, PE21 9QS
Actively Recruiting
167
University College London Hospital ( Site 0527)
London, London, City of, United Kingdom, NW1 2PG
Active, Not Recruiting
168
Guy's & St Thomas' NHS Foundation Trust ( Site 0523)
London, London, City of, United Kingdom, SE1 9RT
Active, Not Recruiting
169
Hammersmith Hospital ( Site 0533)
London, London, City of, United Kingdom, W12 OHS
Actively Recruiting
170
Freeman Hospital ( Site 0532)
Newcastle upon Tyne, United Kingdom, NE7 7DN
Actively Recruiting
171
Royal Gwent Hospital ( Site 0524)
Newport, United Kingdom, NP20 2EF
Actively Recruiting
Research Team
T
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How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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