Actively Recruiting
Using Autologous Bone Marrow Aspirate Concentrate to Treat Complete Anterior Cruciate Ligament Tear
Led by abdulmajeed hammadi · Updated on 2025-08-07
20
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
This research aims to evaluate the use of autologous bone marrow aspirate concentrate (BMAC) to treat anterior cruciate ligament (ACL) tears, focusing on partial and complete tears without retraction. The ACL is essential for knee stability and is commonly injured in athletes. Traditional treatments vary from conservative care for partial tears to surgery for complete tears, but this study explores a regenerative medicine approach using BMAC to potentially promote healing and restore knee function. Participants receive a local injection of 4 cc of autologous bone marrow aspirate concentrate into the injured knee joint. The bone marrow is collected from the patient under local or general anesthesia by aspirating about 1-2 cc/kg of body weight, concentrated using centrifugation and a special disposable kit, then injected under ultrasound guidance in a sterile field. This is a single-arm study conducted at multiple centers. During the 6-month study, participants will undergo clinical assessments of ACL function and overall knee stability every 12 weeks. Magnetic resonance imaging (MRI) of the knee will be performed at 6 months to monitor structural changes. The study tracks functional recovery and joint stability to assess the potential benefits of BMAC treatment in ACL tears.
CONDITIONS
Brief Title
Bone Marrow Aspirate Concentrate for Anterior Cruciate Ligament Tear Treatment.
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Confirmed diagnosis of complete or partial ACL tear via clinical examination and imaging studies
- Aged between 20 and 55 years
You will not qualify if you...
- History of bleeding disorders
- History of malignancy
- Critically ill patients or those with comorbidities
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
Duration - Single treatment with follow-up assessments over 6 months
Participants receive an injection of autologous bone marrow aspirate concentrate into the injured knee under local anesthesia and ultrasound guidance to promote healing of the ACL tear.
1 treatment visit and follow-up visits every 12 weeks for up to 6 months
Trial Site Locations
Total: 1 location
1
Ministry of Health
Baghdad, Iraq, 964
Actively Recruiting
Research Team
A
abdulmajeed A hammadi, MD
K
khalil J kareem, MD
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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