Bone Marrow Aspirate Versus Platelet-Rich Fibrin for the Treatment of Plantar Fasciitis - A Double-Blind Randomized Clinical Trial

What this Trial Is About

Researchers are evaluating two different injections for treating chronic plantar fasciitis, a common cause of heel pain that persists despite usual treatments like physical therapy or steroid injections. This trial compares autologous bone marrow aspirate and platelet-rich fibrin injections to see their effects on pain and foot function, using ultrasound guidance to ensure accurate delivery. The study is randomized, double-blind, and focuses on both clinical outcomes and imaging changes in the plantar fascia. Participants receive a single ultrasound-guided injection of either bone marrow aspirate, taken from the back of the pelvic bone under local anesthesia, or platelet-rich fibrin prepared from their own blood. Both injections are performed after regional anesthesia of the tibial nerve and under sterile conditions. The trial includes two groups, each receiving one of these treatments on the plantar fascia of the affected foot. During the study, participants will be monitored for pain levels using the Visual Analog Scale and for any adverse events at multiple time points up to 24 months. Foot function is assessed with a special score at several visits, and ultrasound will measure plantar fascia thickness before treatment and one year later. The total follow-up allows researchers to evaluate both safety and effectiveness over time, contributing to understanding these regenerative therapies for heel pain.

Bone Marrow Aspirate Versus Platelet-Rich Fibrin for the Treatment of Chronic Plantar Fasciitis