Actively Recruiting
Bone Marrow Aspirate Versus Platelet-Rich Fibrin for the Treatment of Chronic Plantar Fasciitis
Led by Federal University of São Paulo · Updated on 2025-11-21
72
Participants Needed
1
Research Sites
156 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This randomized, double-blind clinical trial aims to compare the clinical and imaging effects of autologous bone marrow aspirate versus platelet-rich fibrin injections in patients with chronic plantar fasciitis. The procedures are performed under ultrasound guidance to ensure precision and safety. The study evaluates pain reduction, foot function, and ultrasonographic changes in the plantar fascia at follow-up intervals.
CONDITIONS
Official Title
Bone Marrow Aspirate Versus Platelet-Rich Fibrin for the Treatment of Chronic Plantar Fasciitis
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adults aged 18 to 75 years
- Clinical diagnosis of chronic plantar fasciitis for more than 6 months confirmed by ultrasonography
- Persistent heel pain not improved by stretching, orthotics, physical therapy, or corticosteroid injections
- Visual Analog Scale (VAS) pain score of 4 or higher at baseline
- Ability and willingness to follow study procedures and attend follow-up visits
- Signed informed consent
You will not qualify if you...
- Previous foot or ankle surgery on the affected limb
- Acute trauma, infection, or ulceration near the plantar fascia
- Systemic inflammatory diseases such as rheumatoid arthritis, lupus, or psoriatic arthritis
- Metabolic or endocrine conditions affecting healing, including poorly controlled diabetes or thyroid disorders
- Current use of systemic corticosteroids, immunosuppressants, or anticoagulants
- Active cancer or blood disorders
- Pregnancy or breastfeeding
- Peripheral vascular disease or neuropathy in the lower limbs
- Allergy or contraindication to local anesthesia or blood drawing procedures
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Federal University of São Paulo - Hospital São Paulo
São Paulo, Brazil, 04023-900
Actively Recruiting
Research Team
L
LUCAS FONSECA, MD
CONTACT
C
Carlos Franciozi, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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