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Study of Vitamin D Levels, Bone Health, and Overweight in Children Aged 3 to 15 with Low-Energy Trauma
Led by Paracelsus Medical University · Updated on 2025-09-03
100
Participants Needed
2
Research Sites
34 weeks
Total Duration
AI-Summary
What this Trial Is About
This research aims to understand the relationship between vitamin D levels, bone metabolism, and obesity in children aged 3 to 15 years who have experienced low-energy trauma. The study compares children with confirmed fractures to those with similar trauma but no fractures to explore factors that may contribute to bone fragility and fracture risk. Participants are divided into two groups children with radiologically confirmed low-energy fractures and children with low-energy trauma but no fractures. Blood samples are collected within seven days of trauma to measure markers such as 25-hydroxyvitamin D, parathyroid hormone, alkaline phosphatase, calcium, and phosphate. Dietary calcium intake and body measurements are also recorded to evaluate nutritional and metabolic status. Children will undergo baseline assessments including body mass index measurement and a dietary questionnaire. Researchers analyze blood markers and calculate a composite bone risk score to identify factors linked to fracture risk. The study uses statistical methods to compare groups and assess the association between bone markers and fractures, aiming to improve understanding of pediatric bone health and inform prevention strategies.
CONDITIONS
Brief Title
Bone Outcomes, Obesity, Sunlight, and Trauma in Children
Research Team
A
Andrea Cosentino, MD
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