Evaluating Platelet-Rich Fibrin for Bone Healing After Jaw Cyst Surgery

What this Trial Is About

This clinical trial evaluates the use of autologous platelet-rich fibrin PRF to promote bone regeneration after cystic enucleation in the jaws. The study compares the healing outcomes of PRF treatment to conventional surgical management in patients with odontogenic cysts. It aims to assess whether PRF, a material rich in growth factors, can enhance the bone healing process following surgery. Participants undergoing cystic enucleation will be randomly assigned to one of two groups. One group will receive PRF prepared from their own blood, applied directly to the bone defect during surgery. The other group will receive standard surgical treatment without PRF. Both groups will have their osseous defects managed according to their assigned procedure. Participants will be monitored through clinical and radiographic assessments to measure bone regeneration and healing rates. The primary outcome is radiographic bone regeneration six months after surgery. The study requires follow-up visits to evaluate healing progress, with participation lasting through the initial surgery and subsequent monitoring period.

Bone Regeneration Using PRF After Cyst Enucleation