Actively Recruiting
Study to Identify and Develop Probiotics That Increase Butyrate Production for Better Gut Health and Microbiota Balance in Adults Aged 20 to 80
Led by Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement · Updated on 2025-12-16
25
Participants Needed
1
Research Sites
N/A
Total Duration
AI-Summary
What this Trial Is About
Researchers are investigating how probiotics that increase butyrate production can improve gut health and balance the microbiota. Butyrate is a key short-chain fatty acid that supports intestinal cells, strengthens the gut barrier, and reduces inflammation. The study focuses on adults aged 20 to 80 years and explores the link between butyrate production and beneficial effects on digestion, immunity, and overall wellness. The study involves isolating and identifying probiotic bacterial strains from stool samples that are known to produce or stimulate butyrate production. This observational research will monitor these strains over up to three years to understand how they interact with the microbiota and the host. No specific treatments or interventions are administered, as this is a study of natural bacterial populations. Participants will provide stool samples for bacterial analysis using gene sequencing methods. Researchers will measure the number of butyrate-producing strains present and evaluate their potential benefits. The study also tracks participants health, diet, and lifestyle factors such as exercise and body mass index. The goal is to develop probiotic products based on these findings to support gut health.
CONDITIONS
Brief Title
Boosting Microbiota Butyrate Producers to Improve Gut Health
Research Team
R
REBECA MARTIN ROSIQUE, PhD
E
ELISE BOREZEE, PhD
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