Actively Recruiting
Boosting Microbiota Butyrate Producers to Improve Gut Health
Led by Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement · Updated on 2025-12-16
25
Participants Needed
1
Research Sites
153 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The human gut microbiota is a dynamic ecosystem essential to health, influenced by diet, age, and lifestyle. It plays a key role in digestion, immunity, and nervous system regulation. Among its important compounds, short-chain fatty acids, particularly butyrate, are crucial for intestinal and metabolic balance, as they support homeostasis, strengthen the epithelial barrier, and have anti-inflammatory effects. An imbalance in the microbiota, especially a decrease in butyrate-producing bacteria, is linked to intestinal, metabolic, and neurological disorders. A fiber-rich diet promotes the growth of these beneficial bacteria. This study aims to isolate and characterize probiotics that can enhance butyrate production, thereby improving intestinal health and microbiota balance. Sampling conditions will comply with regulations governing research involving human subjects.
CONDITIONS
Official Title
Boosting Microbiota Butyrate Producers to Improve Gut Health
Who Can Participate
Eligibility Criteria
You may qualify if you...
- People between 20 and 80 years old in good health with a body mass index between 18.5 and 30 kg/m²
- Not deprived of liberty or under guardianship
- For ages 20 to 60: Exercise at least twice a week or follow a flexitarian diet
- For ages 20 to 60: No known chronic conditions
- For ages 20 to 60: Not undergoing chronic treatment
You will not qualify if you...
- Under 20 or over 80 years old
- Part of the principal investigator's team or reporting to the investigator
- Antibiotic therapy within 3 months prior to sampling
- Taken probiotics or synbiotics within 15 days prior to sampling
- Body mass index below 18.5 or above 30 kg/m²
- Deprived of liberty or under guardianship
- For ages 20 to 60: Not exercising twice a week or not following a flexitarian diet
- For ages 20 to 60: Having a chronic illness or undergoing chronic treatment
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
INRAE
Jouy-en-Josas, France, 78350
Actively Recruiting
Research Team
R
REBECA MARTIN ROSIQUE, PhD
CONTACT
E
ELISE BOREZEE, PhD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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