Born In Guangzhou Intervention Study Combining Dietary, Physical Activity, and Lifestyle Changes During Pregnancy to Improve Maternal and Infant Outcomes

What this Trial Is About

Researchers are evaluating a package of interventions combining diet, physical activity, and lifestyle changes during pregnancy to improve outcomes for mothers and their infants. This study focuses on pregnant women and aims to measure effects on pregnancy complications, child development, and maternal health over an extended period. The study is sponsored by Guangzhou Women and Children's Medical Center and involves behavioral intervention rather than drug treatment. Participants are randomly assigned to either a proactive management group receiving guidance on balanced diet, sufficient exercise, and lifestyle adjustments such as sleep and sun exposure, or to a group receiving standard prenatal care without extra intervention. The intervention is designed to begin before 20 weeks of pregnancy and continues through delivery and postpartum periods. During the study, mothers and children will undergo assessments including measurements of maternal weight change during pregnancy until one month postpartum, newborn size and skinfold thickness at birth, and long-term tracking of blood lipid, glucose, and insulin profiles up to six years after delivery. Child growth and neurological development are evaluated at multiple time points including six months, one year, three years, and six years of age. Maternal physical strength and body composition are also monitored around delivery. The study involves a double-blind design with long-term follow-up to monitor safety and effectiveness outcomes.

Born In Guangzhou Intervention Study