In-utero co-exposure to toxic metals and micronutrients on childhood risk of overweight or obesity: new insight on micronutrients counteracting toxic metals.
Wanyu Huang, Tak Igusa, Guoying Wang...
https://pubmed.ncbi.nlm.nih.gov/35589962/Actively Recruiting
Led by Johns Hopkins Bloomberg School of Public Health · Updated on 2025-09-17
24000
Participants Needed
1
Research Sites
N/A
Total Duration
This research aims to understand how early life exposures affect health outcomes in both mothers and children. It focuses on a wide range of factors starting from birth and tracks their impact on pediatric and adult health. The study is observational and investigates pregnancy complications, birth outcomes such as preterm birth and birthweight, as well as long-term child and maternal health up to 21 years after delivery. Participants include women who deliver a single live infant at Boston Medical Center, either preterm or full term with varying birthweights. The study involves enrolling mother-child pairs and following them from birth until the child reaches 21 years of age. Data collection includes high-quality biospecimen sampling, detailed questionnaires, clinical measurements, and review of electronic medical records. Throughout the study, participants undergo comprehensive health assessments and data collection to monitor pregnancy complications at birth, birth outcomes, and ongoing child and maternal health outcomes. Researchers measure these outcomes from birth through 21 years, aiming to identify factors influencing long-term health. The studys long follow-up period allows for extensive observation of health developments in both mother and child.
CONDITIONS
Boston Birth Cohort Study
X
Xiaobin Wang, MD, ScD
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Johns Hopkins Bloomberg School of Public Health
Lead Sponsor
Boston Medical Center
Collaborating Sponsor
You may qualify if you...
You will not qualify if you...
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - At birth
Participants undergo assessments at birth including collection of biospecimens and clinical data related to pregnancy complications and birth outcomes.
1 visit (in-person)
Duration - From birth to 21 years
Participants are followed postnatally from birth to age 21 years to monitor child and maternal health outcomes through questionnaires, measurements, and medical record reviews.
Periodic visits over 21 years, including standardized interviews and measurements
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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https://pubmed.ncbi.nlm.nih.gov/37947096/Johns Hopkins Bloomberg School of Public Health
Lead Sponsor
Boston Medical Center
Collaborating Sponsor