Actively Recruiting

Age: 18Years - 75Years
All Genders
NCT07240337

Botulinum Toxin Applications in Hemiplegic Patients

Led by Istanbul Physical Medicine Rehabilitation Training and Research Hospital · Updated on 2025-11-20

34

Participants Needed

1

Research Sites

4 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This retrospective study will be conducted by reviewing the medical records of hemiplegic patients who received botulinum toxin treatment between 2017 and 2020 at the Physical Medicine and Rehabilitation outpatient clinic of Istanbul Physical Medicine and Rehabilitation Training and Research Hospital. A total of 35 hemiplegic patients who underwent botulinum toxin injection and had at least two follow-up records (with a 6-month interval) will be included. Sociodemographic and clinical data, stroke-related characteristics, botulinum toxin dosage, injected muscle groups, medications, and comorbidities will be recorded. Functional assessments, including the Functional Independence Measure (FIM) and Brunnstrom stage, as well as spasticity evaluations using the Modified Ashworth Scale and the Global Spasticity Index, will be obtained from patient files.

CONDITIONS

Official Title

Botulinum Toxin Applications in Hemiplegic Patients

Who Can Participate

Age: 18Years - 75Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Aged between 18 and 75 years with a clinical diagnosis of hemiplegia
  • Received botulinum toxin injections for upper and/or lower limb spasticity
  • Have recorded data for two time points including Functional Independence Measure, Brunnstrom stage, Modified Ashworth Scale, and Global Spasticity Index
  • Documentation available of injected muscles and total botulinum toxin dosage administered
Not Eligible

You will not qualify if you...

  • Missing essential data such as Functional Independence Measure, Modified Ashworth Scale, Global Spasticity Index, or Goal Attainment Scale at either visit
  • Underwent major interventions during follow-up like surgery or started intrathecal baclofen pump therapy
  • Have severe neurological disorders that interfere with assessment, such as progressive neurodegenerative diseases

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

İstanbul Physical Medicine and Rehabilitation Research and Training Hospital

Istanbul, Bahcelievler, Turkey (Türkiye), 34147

Actively Recruiting

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How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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