Actively Recruiting
Botulinum Toxin in Raynaud's Phenomenon
Led by Emory University · Updated on 2025-02-12
36
Participants Needed
1
Research Sites
198 weeks
Total Duration
On this page
Sponsors
E
Emory University
Lead Sponsor
A
American Society for Surgery of the Hand
Collaborating Sponsor
AI-Summary
What this Trial Is About
Raynaud's Phenomenon (RP) is the most common vasospastic disorder encountered by hand surgeons with an estimated prevalence of 5% in the general population. It's manifestations are broad, and can range from minor to severe. Sometimes it can be refractory to treatments. The goal of this study is to evaluate the efficacy of Botulinum toxin (BT) in the treatment of treatment refractory RP by objective and subjective measures.
CONDITIONS
Official Title
Botulinum Toxin in Raynaud's Phenomenon
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 18 or older
- Patients with moderate to severe Raynaud's Phenomenon not controlled after 3 months of standard medical therapy
- Patients with severe Raynaud's Phenomenon showing evidence of tissue loss
You will not qualify if you...
- Patients under 18 years old
- Previous Botulinum toxin treatment for Raynaud's Phenomenon within the past year
- Active infection at the treatment site including cellulitis, fever, chills, or elevated inflammatory markers
- Prior digital sympathectomy surgery for Raynaud's Phenomenon
- Changes to medical treatment for Raynaud's Phenomenon within the past 4 weeks
- Allergy or contraindication to Botulinum toxin injection
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Emory University Hospital
Atlanta, Georgia, United States, 30322
Actively Recruiting
Research Team
P
Paul A Ghareeb, MD
CONTACT
A
Anthony Karzon
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
3
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