Actively Recruiting
Botulinumtoxin A as a Treatment for Myalgia and Myofacial Pain in Patient With Temporomandibulardisorders
Led by Region Stockholm · Updated on 2025-04-24
90
Participants Needed
1
Research Sites
82 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Both patients and remitters ask for treatment with Botulinumtoxin A (BTX) with the hope that it will be an effective aid for pain, but little is known regarding if the effect is dose dependent. The aim of this project is to investigate if injections with BTX in the masseter- and temporal muscle is an efficient treatment in patient with myogenous temporomandibular disorders (TMD) and if the effect of BTX is dose dependent.
CONDITIONS
Official Title
Botulinumtoxin A as a Treatment for Myalgia and Myofacial Pain in Patient With Temporomandibulardisorders
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Written consent given
- Diagnosis of myalgia, myofacial pain, or myofascial pain with referred pain
- Average pain score of 3 or higher for more than three months
- Palpation pain in masseter or temporalis muscles
- No orofacial pain treatment within the past three months
- Use of adequate contraceptives and negative pregnancy test
- Presence of co-diagnoses such as disc displacement with or without reduction, degenerative joint disease, or arthralgia allowed
You will not qualify if you...
- Botulinum toxin treatment within the last 12 months
- Orofacial pain treatment within the last 3 months
- Systemic inflammatory diseases like rheumatoid arthritis, psoriatic arthritis, or ankylosing spondylitis
- Widespread pain conditions such as fibromyalgia
- Neuropathic pain
- Neurologic diseases like myasthenia gravis
- Pain caused by dental issues
- Use of muscle relaxants or aminoglycoside antibiotics
- Pregnancy or nursing
- Hypersensitivity to Botulinum toxin
- Neuropsychiatric conditions
- Difficulty understanding the Swedish language
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Eastman institute Folktandvården Region Stockholm
Stockholm, Sweden, 11324
Actively Recruiting
Research Team
V
Veronica de Flon
CONTACT
H
Hajer Jasim
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
OTHER
Number of Arms
2
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here