Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT06307392

Bougie Versus Endotracheal Tube Alone on First-attempt Intubation Success in Prehospital Emergency Intubation (BETA Trial)

Led by Nantes University Hospital · Updated on 2026-01-23

710

Participants Needed

10

Research Sites

157 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Emergency intubation is routinely performed in the prehospital setting. Airway management in the prehospital setting has substantial challenges, such as hostile environment or lack of technical support in case of first attempt intubation failure, and inherent risk of complications, such as hypoxemia, aspiration or oesophageal intubation. This risk is higher when several attempts are needed to succeed endotracheal intubation. Thus, a successful first attempt intubation is highly desirable to avoid adverse intubation-related events. Noteworthy, prehospital emergency intubation is associated with a lower rate of first attempt intubation success when compared to emergency intubation in the emergency department (ED). Research is needed to overcome the specific challenges of airway management in the prehospital setting, and to improve the safety and efficiency of prehospital emergency intubation. Literature reports that the use of assistive devices such as bougie may increase the rate of first-attempt intubation success in the ED. To date, no randomized trial has ever studied this device in the prehospital setting. Thus, the aim of the BETA trial is to compare first attempt intubation success facilitated by the bougie versus the endotracheal tube alone in the prehospital setting.

CONDITIONS

Official Title

Bougie Versus Endotracheal Tube Alone on First-attempt Intubation Success in Prehospital Emergency Intubation (BETA Trial)

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Managed by a physician staffed mobile intensive care unit (MICU)
  • Indication for emergency prehospital endotracheal intubation
  • Age 18 years or older
Not Eligible

You will not qualify if you...

  • Pregnant women
  • Patients with a "not to be resuscitated" indication
  • Patients with predictors of difficult intubation for whom bougie use is indicated on first attempt
  • Patients under guardianship, trusteeship, or safeguard of justice
  • Patients without health insurance

AI-Screening

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Trial Site Locations

Total: 10 locations

1

Nantes University Hospital

Nantes, Loire Atlantique, France, 44093

Actively Recruiting

2

CHU de Besançon

Besançon, France, 25000

Actively Recruiting

3

CHU de Bordeaux

Bordeaux, France, 33000

Actively Recruiting

4

CHU de Clermont-Ferrand

Clermont-Ferrand, France, 63000

Actively Recruiting

5

CHD La Roche sur Yon

La Roche-sur-Yon, France, 85925

Actively Recruiting

6

CH de Lorient

Lorient, France, 56100

Not Yet Recruiting

7

CHU de Lyon

Lyon, France, 69003

Not Yet Recruiting

8

CHU de Nancy

Nancy, France, 54000

Actively Recruiting

9

CHU de Poitiers

Poitiers, France, 86000

Actively Recruiting

10

CHU de Rennes

Rennes, France, 35000

Actively Recruiting

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Research Team

Q

Quentin LE BASTARD, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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