Comparing Nerve Block and Haematoma Block for Wrist Fracture Realignment in Adults A Multicenter Randomized Study on Distal Radius Fracture Treatment

What this Trial Is About

Researchers are evaluating the benefits and risks of using an ultrasound-guided brachial plexus nerve block compared to a haematoma block for adults with distal radius wrist fractures who need realignment of the broken bone without surgery closed reduction. This study is a Phase 4 multicenter randomized controlled trial aiming to compare these two anesthesia methods to improve care for wrist fractures. Participants will be randomly assigned to receive either an ultrasound-guided brachial plexus nerve block or the standard haematoma block during the closed reduction procedure. The nerve block involves administering 30 ml of lidocaine with adrenaline through multiple injections near the brachial plexus, either via a lateral infraclavicular or axillary approach. The haematoma block group will receive local anesthesia with or without additional sedation or pain relief as per local practices. During the study, researchers will monitor participants for 90 days after the closed reduction to assess the need for surgery, complications related to treatment, wrist function using the Patient Rated Wrist Evaluation PRWE, pain levels during the procedure, and the quality of the fracture alignment immediately after treatment. Participants will be closely followed with these evaluations to understand the effectiveness and safety of each anesthesia method, with the total participation lasting at least 3 months after the procedure.

Brachial Plexus Nerve Block Versus Haematoma Block for Closed Reduction of Distal Radius Fracture in Adults - The BLOCK Trial. A Multicentre Randomised Controlled Trial.