Actively Recruiting
Brain [18F]-FES PET/CT in Patients With Estrogen-Receptor Positive Breast Cancer
Led by Weill Medical College of Cornell University · Updated on 2025-11-24
20
Participants Needed
1
Research Sites
205 weeks
Total Duration
On this page
Sponsors
W
Weill Medical College of Cornell University
Lead Sponsor
G
GE Healthcare
Collaborating Sponsor
AI-Summary
What this Trial Is About
The goal of this interventional study is to optimize the protocol of FES PET/CT in Estrogen Receptor positive Breast cancer patients with Brain metastases. Patients will undergo MRI of the brain and FDG PET/CT brain as part of standard of care for radiation treatment planning. An additional 18F-FES PET/CT brain scan will be completed before this standard of care radiation treatment. Patients will be followed prospectively with clinical and MRI assessments per standard-of-care for a total of 12 months. Study Population: Patients with ER-positive breast cancer with biopsy proven or suspected new or recurrent brain metastases (based on standard of care MRI) planned for radiation treatment of brain lesions.
CONDITIONS
Official Title
Brain [18F]-FES PET/CT in Patients With Estrogen-Receptor Positive Breast Cancer
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Diagnosis of estrogen receptor-positive breast cancer confirmed by biopsy with new or recurrent brain metastases confirmed by biopsy or suspected by MRI
- Able to provide informed consent
- Stopped estrogen receptor modulators at least 8 weeks ago and estrogen receptor down regulators at least 28 weeks ago
- At least 18 years old
- Eastern Cooperative Oncology Group performance score of 0 or 1
- Expected to live at least 6 months
- Planned for radiation treatment of brain metastases
You will not qualify if you...
- Pregnant
- Unable to undergo standard of care procedures
- Allergy to 18F-FES radiotracer
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
New York-Presbyterian/Weill Cornell Medical Center
New York, New York, United States, 10021
Actively Recruiting
Research Team
J
Jana Ivanidze, MD/PhD
CONTACT
A
Alexis Watson
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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