Actively Recruiting

Phase Not Applicable
Age: 18Years - 45Years
MALE
Healthy Volunteers
NCT06570135

Brain Activity During Sexual Behavior in Patients With Primary Premature Ejaculation a Clinical Trial

Led by Xijing Hospital · Updated on 2025-04-17

20

Participants Needed

2

Research Sites

38 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This is a controlled study of patients with and without primary premature ejaculation. It is based on near-infrared spectroscopy (NIRS) functional brain imaging to detect and compare changes in brain activity in resting and task states (Simulated Sex) between the two groups of patients.

CONDITIONS

Official Title

Brain Activity During Sexual Behavior in Patients With Primary Premature Ejaculation a Clinical Trial

Who Can Participate

Age: 18Years - 45Years
MALE
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Men aged 18 to 45 years
  • Meet the 2014 International Society for Sexual Medicine (ISSM) criteria for primary premature ejaculation (PPE)
  • Have a stable, heterosexual relationship with a single sexually active female partner for at least 6 months
  • Have at least two sexual intercourses per week and maintain this during the study
  • Have premature ejaculation lasting longer than 6 months
  • Score higher than 9 on the Chinese version of Premature Ejaculation Diagnostic Tool (PEDT)
  • Have no history of previous therapies for premature ejaculation or stopped such therapies at least 3 months prior
  • Provide signed informed consent
  • For non-PPE group: men aged 18-45 years matched by age within 3 years to PPE group
  • Do not meet the 2014 ISSM criteria for premature ejaculation
  • Stable, heterosexual relationship with a single sexually active female partner for at least 6 months
  • Provide signed informed consent
Not Eligible

You will not qualify if you...

  • Diagnosed with secondary, variable, or subjective premature ejaculation
  • Using medications for endocrinological, metabolic, chronic systemic, or psychiatric diseases
  • Abusing alcohol or illegal drugs
  • Diagnosed with erectile dysfunction (score less than 21 on IIEF-5)
  • Diagnosed with sexual hormone abnormalities, hyperthyroidism, hypothyroidism, Peyronie's disease, prostatitis, urethritis, or urinary tract infection
  • Head injuries preventing completion of near-infrared brain function imaging
  • Severe schizophrenia, anxiety, depression, or other neurological symptoms
  • Poor compliance with study procedures

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 2 locations

1

Air Force Military Medical University

Xi'an, Shaanxi, China, 70032

Actively Recruiting

2

Air Force Military Medical University

Xi'an, Shaanxi, China, 70032

Actively Recruiting

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Research Team

W

Weijun Qin, M.D

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NON_RANDOMIZED

Model

PARALLEL

Primary Purpose

BASIC_SCIENCE

Number of Arms

2

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