Actively Recruiting
Brain-Computer Interfaces in Laryngeal Dystonia
Led by Kristina Simonyan · Updated on 2025-12-02
40
Participants Needed
1
Research Sites
280 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The researchers will develop and evaluate the use of adaptive closed-loop brain-computer interface therapeutic intervention in laryngeal dystonia.
CONDITIONS
Official Title
Brain-Computer Interfaces in Laryngeal Dystonia
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Clinically documented isolated adductor laryngeal dystonia (ADLD) without other dystonia or tremor forms
- Healthy controls without neurological, psychiatric, or laryngeal problems
- Age between 18 and 80 years
- Native English speakers only
- Right-handed individuals only
- Normal cognitive status based on Montreal Cognitive Assessment
You will not qualify if you...
- Unable to give informed consent
- Pregnant or breastfeeding women until no longer pregnant or breastfeeding
- History of neurological problems other than ADLD, psychiatric disorders, or laryngeal diseases like vocal fold paralysis or carcinoma
- Impaired hearing, vision, or speaking abilities except from ADLD
- Presence of dystonia symptoms at rest
- Currently asymptomatic due to botulinum toxin treatment; must be at least three months post-injection
- Use of medications affecting the central nervous system
- Implanted deep brain stimulators
- History of brain or laryngeal surgeries such as thyroplasty or selective laryngeal adductor denervation-reinnervation
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Massachusetts Eye and Ear Infirmary
Boston, Massachusetts, United States, 02114
Actively Recruiting
Research Team
K
Kristina Simonyan, MD, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
TRIPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
OTHER
Number of Arms
2
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