Actively Recruiting
Brain Connections for Arm Movement After Stroke
Led by VA Office of Research and Development · Updated on 2025-06-13
76
Participants Needed
1
Research Sites
385 weeks
Total Duration
On this page
Sponsors
V
VA Office of Research and Development
Lead Sponsor
V
VA Pittsburgh Healthcare System
Collaborating Sponsor
AI-Summary
What this Trial Is About
The purpose of this study is to use Transcranial Magnetic Stimulation (TMS) while subjects are making reaching movements in a robotic arm device in order to discover how different brain areas control movement before and after stroke and when these brain areas are most sensitive to TMS.
CONDITIONS
Official Title
Brain Connections for Arm Movement After Stroke
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Be between 45 and 90 years of age
- Have adequate language and neurocognitive function to participate in training and testing
- Be medically stable to participate in the study
- Be English speaking
- For participants with stroke: Clinically defined, unilateral, hemiparetic stroke with radiologic exclusion of other diagnoses
- Stroke onset at least 6 months prior to enrollment
- Subcortical stroke affecting areas such as the internal capsule or deep white matter of posterior frontal lobe
- Present with mild to moderate arm dysfunction
You will not qualify if you...
- Unable to give informed consent
- Have a serious complicating medical illness that would prevent participation
- Have contractures or orthopedic problems limiting joint motion or other impairments interfering with study activities
- Have visual loss that prevents seeing test patterns on the robot computer monitor
- Unable to comply with study requirements
- Currently enrolled in another greater-than-minimal risk study
- Have medical conditions or implants that prevent safe administration of TMS or MRI
- Pregnancy
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
VA Pittsburgh Healthcare System University Drive Division, Pittsburgh, PA
Pittsburgh, Pennsylvania, United States, 15240
Actively Recruiting
Research Team
A
Amy Boos
CONTACT
G
George F Wittenberg, MD PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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