Actively Recruiting
Brain Development in Young Children Following Mild Traumatic Brain Injury - Pilot Study
Led by Institut National de la Santé Et de la Recherche Médicale, France · Updated on 2026-03-05
60
Participants Needed
1
Research Sites
125 weeks
Total Duration
On this page
Sponsors
I
Institut National de la Santé Et de la Recherche Médicale, France
Lead Sponsor
I
Institut National de Recherche en Informatique et en Automatique
Collaborating Sponsor
AI-Summary
What this Trial Is About
Concussions (also known as mild traumatic brain injury) are common in young children. In some children, they can lead to short- and long-term difficulties. However, our knowledge of the exact consequences of injuries on young children's brains and behavior is limited. These consequences may be different in children under 6, as their brains are fragile and undergoing significant developmental changes. The aim of this study is to determine the extent to which a concussion sustained before the age of 6 years is associated with changes in young children's brain structure, function and behaviours, using a brain imaging. In this study, the results of a group of 30 children with a concussion will be compared to those of 30 children of the same age with an orthopaedic injury to the upper or lower limbs.
CONDITIONS
Official Title
Brain Development in Young Children Following Mild Traumatic Brain Injury - Pilot Study
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Children aged between 36 months (3 years) and 71 months and 31 days (5 years; before their 6th birthday)
- Presentation to the emergency department within 48 hours after injury
- For patient group: documented unintentional non-penetrating head injury and diagnosis of mild traumatic brain injury (WHO pediatric criteria)
- For control group: documented unintentional trauma to an upper or lower limb and diagnosis of simple fracture, sprain, contusion, or mild unspecified limb trauma
You will not qualify if you...
- Previous traumatic brain injury of any severity or age
- Intentional injury
- Use of sedative drugs affecting brain function
- Complications following injury
- Contraindications for MRI
- Parent not fluent in French
- Prematurity
- Severe neurological, developmental, or psychiatric disorders
- Child in foster care at recruitment
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Unité des urgences médicochirurgicales CHU Rennes
Rennes, France, 35200
Actively Recruiting
Research Team
F
Fanny DÉGEILH, PhD
CONTACT
V
Véronique CHASLE, MD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here