Actively Recruiting
Brain Network Analysis of Anesthesia Characteristics in Patients With pDoC Based on PSG
Led by Beijing Tiantan Hospital · Updated on 2024-08-01
60
Participants Needed
1
Research Sites
124 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The goal of this prospective, exploratory and observational study is to learn about in healthy volunteers and patients with prolonged disorders of consciousness(pDoC). The main questions it aims to answer are: 1. Observe the similarities and differences of polysomnography between pDoC patients and healthy volunteers, and analyze the characteristic brain network changes based on polysomnography 2. To observe the similarities and differences of polysomnography in pDoC patients before and after Insertion of spinal cord electric stimulator under general anesthesia,and analyze the changes of anesthesia characteristic brain network in patients with consciousness disorders based on polysomnography. 3. To observe the similarities and differences of polysomnography in pDoC patients before and after spinal cord stimulation,and analyze the characteristic changes of brain network after spinal cord stimulation. We will record the 8h polysomnography of healthy volunteers,record the polysomnography of DOC patients before and 24 hours after operation;and record the 24h polysomnography of patients with spinal cord electric stimulator.
CONDITIONS
Official Title
Brain Network Analysis of Anesthesia Characteristics in Patients With pDoC Based on PSG
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Healthy volunteers aged 18 to 65 years, native Chinese
- No history of sleep apnea for healthy volunteers
- No history of insomnia for healthy volunteers
- Volunteer consent for healthy volunteers
- Patients aged 18 to 65 years, native Chinese with prolonged disorders of consciousness after acquired brain injury
- Spinal electric stimulator implanted under general anesthesia for patients
- Patient consent obtained
You will not qualify if you...
- Healthy volunteers who took hypnotic drugs within 72 hours before the study
- Continuous sedation treatment within 72 hours before the study
- Brain structure damage such as open head injury or brain tissue resection
- Decreased intracranial compliance caused by hydrocephalus
- Airway narrowing or severe ventilation problems
- Known or suspected serious heart, lung, or kidney dysfunction
- Allergy to sedative drugs
- Other mental or nervous system diseases
- Any other reasons making the participant unsuitable for this study
AI-Screening
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Trial Site Locations
Total: 1 location
1
Beijing Tiantan Hospital
Beijing, China
Actively Recruiting
Research Team
R
Ruquan Han, M.D
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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