Actively Recruiting
Brain-Training Treatment for Long COVID in Older Adults
Led by UConn Health · Updated on 2026-01-08
40
Participants Needed
1
Research Sites
168 weeks
Total Duration
On this page
Sponsors
U
UConn Health
Lead Sponsor
N
National Institute on Aging (NIA)
Collaborating Sponsor
AI-Summary
What this Trial Is About
This research is being done to collect preliminary data on the potential of computerized "brain-training" exercises for treating Long COVID symptoms in older adults. The investigators hypothesize that computerized brain-training will be an acceptable and feasible intervention for treating Long COVID symptoms in older adults. The investigators also expect to provide initial evidence that computerized brain-training has potential for improving thinking, mood, and other aspects of everyday functioning in older adults with Long COVID.
CONDITIONS
Official Title
Brain-Training Treatment for Long COVID in Older Adults
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Prior confirmed COVID-19 infection based on CDC guidelines or a positive test
- Age 60 years or older
- Self-reported cognitive symptoms lasting more than 4 weeks after COVID-19 symptom onset not explained by other diagnoses
- Evidence of subjective cognitive impairment with specific cognitive function test scores or frequent cognitive complaints
- Telephone Interview for Cognitive Status score of 27 or higher
- Fluent in English
- Off psychiatric medications or on a stable dose for at least 1 month before starting the study with no planned dose changes
You will not qualify if you...
- History of neurological disorders or medical conditions affecting cognitive function or study participation (e.g., epilepsy, stroke, dementia, persistent brain injury, structural brain abnormalities)
- Prior diagnosis of Mild Cognitive Impairment or Mild Neurocognitive Disorder unrelated to COVID-19
- Significant psychiatric illnesses per DSM-5 that could interfere with participation or affect results (e.g., schizophrenia, bipolar disorder, major depression with psychotic features, personality disorders)
- Significant neurodevelopmental conditions affecting participation or study results (e.g., intellectual disability, autism spectrum disorder)
- Alcohol or substance use disorder within the past 2 years
- Significant sensory or motor impairments (e.g., blindness) that would interfere with testing or intervention
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
UConn Health
Farmington, Connecticut, United States, 06030
Actively Recruiting
Research Team
H
Holly Eddy, Ph.D., LMFT-S
CONTACT
J
Jennifer Brindisi, M.A.
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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