Actively Recruiting

Phase Not Applicable
Age: 21Years - 39Years
FEMALE
Healthy Volunteers
ID06126627

Neurobiological and Psychobiological Signatures of Vocal Effort in Early Career Teachers

Led by University Hospital, Bonn · Updated on 2025-08-27

100

Participants Needed

1

Research Sites

4 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This research aims to understand primary muscle tension dysphonia, a voice disorder marked by vocal strain and fatigue, which affects quality of life. The study focuses on early career and student female teachers, exploring how stress influences voice and speech control in the brain. Researchers will compare brain imaging, saliva samples, personality traits, and voice muscle activity between teachers with vocal fatigue and those without, to reveal stress-related patterns affecting voice production. Participants are divided into two groups: teachers with vocal fatigue and control participants without vocal fatigue. Both groups undergo two main experiments. The first includes MRI scans with surface electrodes on the neck and audio recordings during stress and non-stress conditions, along with saliva collection and emotional state ratings. The second experiment, about two weeks later, involves speech tasks with neck muscle sensors and audio recordings, accompanied by questionnaires and subjective effort ratings. Throughout the study, participants complete questionnaires on voice, personality, and stress, and provide saliva samples before, during, and after MRI scans. Researchers measure vocal fatigue, brain activity in specific areas, muscle activity in neck muscles, salivary cortisol levels, personality traits, and subjective vocal and cognitive effort. The study lasts about one month, with detailed monitoring to better understand stress's role in vocal fatigue and voice disorders in this population.

CONDITIONS

Brief Title

Brain and Voice Signatures in Teachers

Who Can Participate

Age: 21Years - 39Years
FEMALE
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Female teachers or student teachers in good health with up to 10 years of full-time experience
  • Age between 21 and 39 years
  • For vocal fatigue group: symptoms of vocal fatigue
  • For control group: no symptoms of vocal fatigue
Not Eligible

You will not qualify if you...

  • Left-handedness
  • Smoking in the past 5 years
  • Known vocal fold changes or surgeries and current organic or neurological vocal disorders
  • History of voice therapy
  • Hoarseness
  • Respiratory illnesses, allergies, reflux, or asthma at participation time
  • Hearing disorders or use of hearing aids
  • Psychological, neurological, or endocrinological disorders
  • Use of psychotropic or steroid medications
  • Body mass index over 30
  • Contraindications for MRI such as metal in/on the body
  • Nearsightedness greater than -5 diopters if using only glasses
  • Claustrophobia
  • Pregnancy

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 screening and enrollment visit

Stress induction Behavioral Experiment

Duration - Approximately 2 weeks between experimental sessions

Participants complete questionnaires, practice tasks, and undergo MRI scanning with stress induction including saliva sample collection and emotional state ratings. Approximately 2 weeks later, participants perform speech tasks with sensors and provide subjective ratings of vocal and cognitive effort.

2 visits including MRI session and speech task session

Observation Period

Duration - Up to 1 month

Participants are observed for outcomes such as vocal fatigue, personality measures, and muscle activity through study completion.

No additional visits required

Trial Site Locations

Total: 1 location

1

University Hospital Bonn

Bonn, Germany, 53127

Actively Recruiting

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Research Team

M

Maria Dietrich, PhD

L

Lisa Sindermann, PhD

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NON_RANDOMIZED

Model

PARALLEL

Primary Purpose

BASIC_SCIENCE

Number of Arms

2

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