Actively Recruiting

Age: 30Years - 75Years
FEMALE
Healthy Volunteers
NCT07076147

Breast Cancer Screening Adherence for Women at Moderate Risk for Breast Cancer

Led by University of Southern California · Updated on 2025-12-10

150

Participants Needed

2

Research Sites

156 weeks

Total Duration

On this page

Sponsors

U

University of Southern California

Lead Sponsor

N

National Cancer Institute (NCI)

Collaborating Sponsor

AI-Summary

What this Trial Is About

This study assesses breast cancer screening adherence for women at moderately increased risk for developing breast cancer based on gene mutation status or empiric risk model estimates. It also seeks to determine facilitators and barriers to screening.

CONDITIONS

Official Title

Breast Cancer Screening Adherence for Women at Moderate Risk for Breast Cancer

Who Can Participate

Age: 30Years - 75Years
FEMALE
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Women aged 30 to 75 years
  • Women with either a genetic test showing a moderate risk breast cancer mutation in ATM, CHEK2, BARD1, RAD51C, or RAD51D OR a lifetime breast cancer risk of 20% to 40% based on the Tyrer-Cuzick V8.0B risk model
  • Patients who had breast cancer risk assessments by genetic counselors at USC Norris or LA General Hospital starting in 2021 and at least 12 months before enrollment
  • Women recommended to have annual breast MRI and/or mammogram starting at their genetic counseling risk assessment
  • English or Spanish speaking patients
Not Eligible

You will not qualify if you...

  • History of breast cancer before genetic counseling at USC
  • Diagnosis of any metastatic cancer at the time of genetic counseling risk assessment
  • Deceased patients
  • Patients who had risk reducing mastectomy before their genetic counseling risk assessment

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 2 locations

1

Los Angeles General Medical Center

Los Angeles, California, United States, 90033

Actively Recruiting

2

USC / Norris Comprehensive Cancer Center

Los Angeles, California, United States, 90033

Actively Recruiting

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How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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