Actively Recruiting

Phase Not Applicable
Age: 35Years +
All Genders
ID07091851

A Hybrid Type 1 Randomized Trial of Group Medical Visits and Home Blood Pressure Monitoring Versus Home Blood Pressure Monitoring Alone for Post-Stroke Hypertension

Led by Massachusetts General Hospital · Updated on 2025-09-25

50

Participants Needed

1

Research Sites

13 weeks

Total Duration

On this page

Sponsors

M

Massachusetts General Hospital

Lead Sponsor

A

American Heart Association

Collaborating Sponsor

AI-Summary

What this Trial Is About

Researchers are evaluating two new ways to help people who have had a stroke lower their blood pressure, which is the leading cause of having another stroke and can harm brain health. This study aims to compare home blood pressure monitoring alone with a combination of home monitoring plus group medical visits conducted virtually. The goal is to improve secondary stroke prevention and support brain recovery by testing these two approaches in stroke survivors with hypertension. Participants will be assigned randomly to one of two groups. One group will receive instructions for home blood pressure monitoring only, while the other group will receive the same home monitoring plus participate in virtual group medical visits that provide education and peer support. The study uses a Hybrid Type 1 randomized control trial design to test the effectiveness of these interventions and will measure adoption and acceptability using established research frameworks. During the study, participants will monitor their blood pressure at home and take part in virtual group sessions if assigned to that group. Researchers will assess blood pressure control, focusing on systolic blood pressure measured at three months. The study also includes evaluating how well the interventions are adopted and accepted by participants. Participants must have internet access and a primary care doctor at Massachusetts General Hospital to take part. The study will run until April 2028, with ongoing monitoring and data collection throughout the trial.

CONDITIONS

Brief Title

BRIDGE: Blood Pressure Reduction and Intervention Delivery Via Group Engagement

Who Can Participate

Age: 35Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Adults aged 35 years and older
  • Had a mild to moderate ischemic or hemorrhagic stroke
  • History or new diagnosis of hypertension
  • Ability to read and speak English
  • Have internet access
  • Have an established primary care physician at Massachusetts General Hospital
Not Eligible

You will not qualify if you...

  • Severe stroke (NIH Stroke Scale greater than 15 or Intracerebral Hemorrhage score greater than 3)
  • Discharge to inpatient rehabilitation or skilled nursing facility
  • Diagnosis of dementia
  • Moderate to severe aphasia without a caregiver to consent on their behalf

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person or virtual)

Treatment

Duration - 3 months

Participants engage in home blood pressure monitoring, with some also attending virtual group medical visits to support blood pressure control and stroke prevention.

Regular virtual group visits and home monitoring activities

Trial Site Locations

Total: 1 location

1

Massachusetts General Hospital

Boston, Massachusetts, United States, 02115

Actively Recruiting

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Research Team

N

Nirupama Yechoor, MD, MSc

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

PREVENTION

Number of Arms

1

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