Actively Recruiting

Phase 4
Age: 18Years +
All Genders
NCT07225842

The Bridging Antiplatelet Therapy With Cangrelor 2 Study

Led by University of Florida · Updated on 2026-05-05

50

Participants Needed

1

Research Sites

88 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The primary aim of this study is to determine rates of patients with optimal platelet reactivity range, defined as PRU levels between 85 and 208, when using a (PFT)-guided titration of cangrelor infusion rate (cangrelor titration) compared to 0.75 mcg/kg/min (standard-dose infusion) for bridging.

CONDITIONS

Official Title

The Bridging Antiplatelet Therapy With Cangrelor 2 Study

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients receiving cangrelor infusion at 0.75 mcg/kg/min for at least two hours as part of standard care
  • Age 18 years or older
  • Ability to provide written informed consent
Not Eligible

You will not qualify if you...

  • Need for urgent surgery
  • Confirmed or suspected pregnancy or breastfeeding
  • Use of oral P2Y12 inhibitors, oral anticoagulants, or glycoprotein IIb/IIIa inhibitors within 48 hours
  • Known allergy or contraindication to cangrelor, mannitol, sorbitol, or microcrystalline cellulose

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

University of Florida Jacksonville

Jacksonville, Florida, United States, 32209

Actively Recruiting

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Research Team

L

Luis Ortega-Paz, MD, PhD

CONTACT

A

Andrea Burton, MPH, CCRP

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

1

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