Actively Recruiting
Can Brief Exposure to Hyperoxia Improve Function After Chronic Spinal Cord Injury?
Led by University of Alberta · Updated on 2025-08-26
25
Participants Needed
1
Research Sites
233 weeks
Total Duration
On this page
Sponsors
U
University of Alberta
Lead Sponsor
C
Canadian Institutes of Health Research (CIHR)
Collaborating Sponsor
AI-Summary
What this Trial Is About
This proof-of-principle study will determine if breathing an increased concentration of oxygen above the concentration in normal room air results in changes in the sensory and motor function in people with subacute or chronic, severe spinal cord injury (SCI).
CONDITIONS
Official Title
Can Brief Exposure to Hyperoxia Improve Function After Chronic Spinal Cord Injury?
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Individuals with traumatic spinal cord injury that occurred 3 months or more ago
- Age between 18 and 65 years old
- Classified as ASIA Impairment Scale A, B, or C at discharge
- Injury level between spinal segments C5 and T10
- Able to provide informed, written consent
You will not qualify if you...
- Frequent uncontrolled autonomic dysreflexia
- Uncontrolled high blood pressure
- Cardiac or cardiovascular disease
- Cancer
- Active urinary tract infection
- Active pressure sores
- Signs of deep vein thrombosis in the legs
- Severe swelling of the feet or legs
- Severe cognitive impairment
- Pulmonary dysfunction such as chronic obstructive pulmonary disease or acute respiratory infection
- Any condition worsened by sitting or lying in one position for 2 hours, such as low back pain
- Pregnancy
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
University of Alberta, Clinical Sciences Bldg
Edmonton, Alberta, Canada, T6G 2B7
Actively Recruiting
Research Team
M
Michelle Barnes, PT
CONTACT
J
Jaynie Yang, PT, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
CROSSOVER
Primary Purpose
OTHER
Number of Arms
2
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