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HIPAA Compliant
ISO 27001 Certified

Actively Recruiting

Phase Not Applicable
Age: 18Years - 25Years
All Genders
ID06395389

Development of a Novel Cannabis Brief Intervention for Frequently-Using Emerging Adults Pilot Randomized Trial

Led by Medical University of South Carolina · Updated on 2026-04-09

62

Participants Needed

1

Research Sites

52 weeks

Total Duration

On this page

Sponsors

M

Medical University of South Carolina

Lead Sponsor

N

National Institute on Drug Abuse (NIDA)

Collaborating Sponsor

AI-Summary

What this Trial Is About

Researchers are evaluating two brief interventions aimed at addressing potentially problematic cannabis use in emerging adults aged 18 to 25. Cannabis is widely used among this age group, and frequent use may lead to long-term health, social, and academic or occupational challenges. The study seeks to assess the feasibility, acceptability, and early effectiveness of a novel cannabis brief intervention compared to a health education approach, using rigorous methods to improve intervention quality for this population. The study involves two groups receiving different 2-session brief interventions, each session lasting 40 to 50 minutes and separated by about one week. One group receives health education focusing on sleep hygiene, nutrition, physical activity, stress, and social connection. The other group participates in the Bloom intervention, which includes personalized discussions about values, reasons for cannabis use, and strategies for living in line with personal goals. Participants are randomly assigned to one of these interventions. Participants complete detailed cannabis assessments including biological samples and self-report measures at baseline, immediately after the second session, and at 1-, 3-, and 6-month follow-ups. Saliva samples are collected five times to test for THC and CBD levels. Researchers measure cannabis use patterns, problems related to use, and symptoms of cannabis use disorder. The total participation period extends up to 6 months post-intervention, with regular assessments to monitor changes and safety throughout the study.

CONDITIONS

Brief Title

A Brief Intervention for Cannabis Use

Who Can Participate

Age: 18Years - 25Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Ages 18 to 25 years
  • Self-reported cannabis use on at least 20 days in the past 30 days
  • Positive urine cannabinoid test
Not Eligible

You will not qualify if you...

  • Currently engaged in or seeking treatment for any substance use
  • History of substance use treatment for any substance
  • Severe alcohol use disorder or other substance use disorder requiring higher level care (AUDIT score ≥14 or DUDIT score ≥2 for women, ≥6 for men)
  • Significant or unstable medical or psychiatric problems such as psychosis or mania
  • Significant risk of suicide or homicide
  • Currently pregnant or breastfeeding

Research Team

K

Kathryn Gex, Ph.D.

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