Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
ID07124611

Testing the Feasibility of Psychosocial Oncology Support During Neoadjuvant Therapy for Patients With Localized Pancreatic Cancer

Led by Ohio State University Comprehensive Cancer Center · Updated on 2026-02-19

60

Participants Needed

1

Research Sites

N/A

Total Duration

On this page

AI-Summary

What this Trial Is About

Researchers are evaluating a psychosocial oncology intervention designed to support patients with localized pancreatic cancer undergoing neoadjuvant therapy before surgery. Neoadjuvant therapy, which may include chemotherapy and/or radiation, aims to shrink the tumor and reduce cancer spread, improving surgery success and survival rates. Despite these benefits, this treatment can cause significant physical and emotional side effects, so adding psychosocial support may help improve patients' quality of life during this phase. The study involves patients receiving weekly telehealth sessions with a psychologist for 40 minutes over four weeks, alongside their usual physical therapy and nutritional therapy referrals. This psychosocial care is provided during the neoadjuvant therapy period, with the goal to ease emotional distress and enhance overall well-being. The intervention is tested for feasibility and acceptability, with patients continuing their standard medical treatments throughout. Participants will be monitored for up to one year to assess how well the psychosocial intervention is accepted and its effects on quality of life, mood, worry, and feelings of uncertainty. Researchers will collect data through questionnaires and interviews to evaluate these outcomes. Safety and overall health will also be followed, ensuring comprehensive support while patients prepare for surgery and recovery.

CONDITIONS

Brief Title

A Brief Psychological Intervention to Improve Emotional Well-Being During Neoadjuvant Therapy for Pancreatic Cancer

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Adults 18 years of age or older
  • Newly diagnosed with localized pancreatic ductal adenocarcinoma
  • Planning to start neoadjuvant therapy before surgical removal of the tumor
  • Neoadjuvant therapy and/or surgery may occur at different medical facilities
Not Eligible

You will not qualify if you...

  • Prisoners
  • Unable to provide consent
  • Unlikely to have surgery after neoadjuvant therapy due to anatomy or health status
  • Confirmed or suspected metastatic (spread) disease
  • Already received two or more cycles of chemotherapy

AI-Screening

AI-Powered Screening

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

Outpatient Treatment

Duration - 4 weeks

Participants meet with a psychologist via telehealth for weekly 40-minute psychosocial oncology sessions and attend standard physical therapy and nutritional therapy appointments during neoadjuvant therapy.

Weekly visits via telehealth and additional physical and nutritional therapy appointments

Trial Site Locations

Total: 1 location

1

Ohio State University Comprehensive Cancer Center

Columbus, Ohio, United States, 43210

Actively Recruiting

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Research Team

T

The Ohio State University Comprehensive Cancer Center

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

HEALTH_SERVICES_RESEARCH

Number of Arms

1

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