Actively Recruiting
A Brief Values Intervention to Support Veterans in Early Buprenorphine Treatment
Led by VA Office of Research and Development ยท Updated on 2025-07-17
50
Participants Needed
1
Research Sites
186 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The US Veteran community continues to feel the impact of the overdose crisis, and opioid use disorder (OUD) diagnoses among Veterans continue to rise. Medication treatment (e.g., buprenorphine, methadone, naltrexone) helps prevent relapse and reduce overdose risk, but does not help with the psychological, social, and functional challenges of early recovery. Therapies that focus on interpersonal functioning and community integration may help improve quality of life during this high-risk period. This research project will create and test a brief, values-based treatment to help Veterans improve their interpersonal functioning and community integration during early treatment. This study will have three phases. Phase 1 will involve the development of the treatment and adaptation using interviews with Veterans and VA Providers. Phase 2 will test the treatment with a group of 10 Veterans to make sure the treatment can be delivered as intended, and to make changes to the treatment or study procedures based on Veteran feedback. Finally, Phase 3 will test the treatment compared to usual treatment in a pilot randomized controlled trial with a group of 40 Veterans. This final phase will provide additional information about Veterans' experience of the treatment and study procedures and the preliminary effects of the treatment on quality of life and related outcomes.
CONDITIONS
Official Title
A Brief Values Intervention to Support Veterans in Early Buprenorphine Treatment
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Meets current Diagnostic and Statistical Manual - 5th Edition criteria for moderate to severe opioid use disorder
- Within 12 weeks of starting buprenorphine, methadone, or naltrexone treatment after at least 2 months without treatment
- Able to provide written informed consent
You will not qualify if you...
- Active psychosis or mania
- Suicidal thoughts requiring inpatient hospitalization
- Active substance use needing detoxification
- Cognitive impairment interfering with study participation
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
VA Bedford HealthCare System, Bedford, MA
Bedford, Massachusetts, United States, 01730-1114
Actively Recruiting
Research Team
V
Victoria Ameral, PhD
CONTACT
A
Anne Marie Hernon
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
3
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