Actively Recruiting

Phase Not Applicable
Age: 4Years - 18Years
All Genders
NCT04929899

Bright Ideas - CIN Feasibility Study

Led by The Hospital for Sick Children · Updated on 2025-01-31

75

Participants Needed

4

Research Sites

169 weeks

Total Duration

On this page

Sponsors

T

The Hospital for Sick Children

Lead Sponsor

R

Rutgers Cancer Institute of New Jersey

Collaborating Sponsor

AI-Summary

What this Trial Is About

In this study investigators will determine the feasibility of a future trial comparing chemotherapy-induced nausea control in children with ALL receiving oral 6-mercaptopurine who do and do not receive problem-solving skill training. This is a novel approach to controlling an important and common treatment-related symptom.

CONDITIONS

Official Title

Bright Ideas - CIN Feasibility Study

Who Can Participate

Age: 4Years - 18Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 4 years or older (validated for ages 4 to 18 years)
  • First diagnosis of Acute Lymphoblastic Leukemia (ALL) in maintenance therapy (non-relapsed)
  • Child and guardian speak English, French, or Spanish (PeNAT available in these languages)
  • No physical or cognitive impairments that prevent use of the PeNAT tool
  • Planned to receive oral 6-mercaptopurine chemotherapy
  • Not planned to receive intravenous, intramuscular, subcutaneous, or intrathecal chemotherapy or oral or intravenous corticosteroids during the 7-day study period
Not Eligible

You will not qualify if you...

  • Receiving intravenous, intramuscular, subcutaneous, or intrathecal chemotherapy during the 7-day study period
  • Receiving oral or intravenous corticosteroids during the 7-day study period

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 4 locations

1

Children's Hospital Los Angeles

Los Angeles, California, United States, 90027

Actively Recruiting

2

Rutgers Cancer Institute

New Brunswick, New Jersey, United States, 08901

Actively Recruiting

3

Inova Children's Hospital

Falls Church, Virginia, United States, 22042

Actively Recruiting

4

Hospital for Sick Children

Toronto, Ontario, Canada, M5G 1X8

Actively Recruiting

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Research Team

L

Lee Dupuis, PhD

CONTACT

T

Tadi Hondonga

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

SUPPORTIVE_CARE

Number of Arms

1

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