Actively Recruiting
Bronchial NIR Image-guided Resection
Led by Massachusetts General Hospital · Updated on 2025-11-10
100
Participants Needed
1
Research Sites
729 weeks
Total Duration
On this page
Sponsors
M
Massachusetts General Hospital
Lead Sponsor
S
Society of University Surgeons
Collaborating Sponsor
AI-Summary
What this Trial Is About
This is a clinical trial to evaluate the use of peritumoral injection of near-infrared dye indocyanine green to identify lung lesions and sentinel lymph nodes. The primary purpose is to determine if the use of ICG injected via navigational bronchoscopy, CT-guided or transthoracic allows us to identify the first lymph node that drains from the tumor, and thus would be the most likely site for metastatic disease, and remove it for analysis to improve the ability to detect tumor in this node and to remove this additional site that potentially contains tumor cells. Using this intraoperative imaging technique, we aim to improve the identification of lung nodules for resection and the intraoperative identification of sentinel lymph nodes in the event that a lymphadenectomy is performed.
CONDITIONS
Official Title
Bronchial NIR Image-guided Resection
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients scheduled for video assisted thoracoscopic surgery or thoracotomy for lung lesion removal as advised by their thoracic surgeon
- 18 years of age or older
- Provided signed and dated informed consent before study procedures
You will not qualify if you...
- Pregnant women
- Women of childbearing potential without a negative pregnancy test before study procedures
- Patients with iodine allergies
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Massachusetts General Hospital
Boston, Massachusetts, United States, 01224
Actively Recruiting
Research Team
Y
Yolonda Colson, MD, PhD
CONTACT
I
Isha Mehta Warikoo, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
OTHER
Number of Arms
1
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