Actively Recruiting

Phase 1
Phase 2
Age: 18Years +
All Genders
NCT03097575

Bronchial NIR Image-guided Resection

Led by Massachusetts General Hospital · Updated on 2025-11-10

100

Participants Needed

1

Research Sites

729 weeks

Total Duration

On this page

Sponsors

M

Massachusetts General Hospital

Lead Sponsor

S

Society of University Surgeons

Collaborating Sponsor

AI-Summary

What this Trial Is About

This is a clinical trial to evaluate the use of peritumoral injection of near-infrared dye indocyanine green to identify lung lesions and sentinel lymph nodes. The primary purpose is to determine if the use of ICG injected via navigational bronchoscopy, CT-guided or transthoracic allows us to identify the first lymph node that drains from the tumor, and thus would be the most likely site for metastatic disease, and remove it for analysis to improve the ability to detect tumor in this node and to remove this additional site that potentially contains tumor cells. Using this intraoperative imaging technique, we aim to improve the identification of lung nodules for resection and the intraoperative identification of sentinel lymph nodes in the event that a lymphadenectomy is performed.

CONDITIONS

Official Title

Bronchial NIR Image-guided Resection

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients scheduled for video assisted thoracoscopic surgery or thoracotomy for lung lesion removal as advised by their thoracic surgeon
  • 18 years of age or older
  • Provided signed and dated informed consent before study procedures
Not Eligible

You will not qualify if you...

  • Pregnant women
  • Women of childbearing potential without a negative pregnancy test before study procedures
  • Patients with iodine allergies

AI-Screening

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Trial Site Locations

Total: 1 location

1

Massachusetts General Hospital

Boston, Massachusetts, United States, 01224

Actively Recruiting

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Research Team

Y

Yolonda Colson, MD, PhD

CONTACT

I

Isha Mehta Warikoo, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

OTHER

Number of Arms

1

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