Actively Recruiting

Phase Not Applicable
Age: 40Years +
FEMALE
NCT07413705

BTL-699-2 and HPM-6000UF Devices for the Improvement of Depressive Symptoms and Sexual Function Among Perimenopausal and Postmenopausal Women

Led by BTL Industries Ltd. · Updated on 2026-02-17

60

Participants Needed

3

Research Sites

55 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The goal of this clinical trial is to evaluate if the combined treatment with EXOMIND (BTL-699-2) and EMSELLA (HPM-6000UF) devices is able to improve depressive symptoms and sexual function in women who are perimenopausal or postmenopausal without an alternative medical cause before enrollment in the study and are aged 40 years and older. The main question it aims to answer is: Does the combined treatment with EXOMIND (BTL-699-2) and EMSELLA (HPM-6000UF) devices improve depressive symptoms and urinary incontinence? Participants will be asked to: Undergo twelve treatments Complete the Patient Health Questionnaire-9 Complete the 6-item Hamilton Depression Rating Scale Complete the Greene Climacteric Scale Complete the Therapy Comfort Questionnaire Complete the International Consultation on Incontinence Questionnaire-Urinary Incontinence Short Form Complete the Female Sexual Function Index Complete the Warwick-Edinburgh Mental Wellbeing Scale Complete the Columbia Suicide Severity Rating Scale-Screen version Complete the Subject Satisfaction Questionnaire Complete the Therapy Comfort Questionnaire

CONDITIONS

Official Title

BTL-699-2 and HPM-6000UF Devices for the Improvement of Depressive Symptoms and Sexual Function Among Perimenopausal and Postmenopausal Women

Who Can Participate

Age: 40Years +
FEMALE

Eligibility Criteria

Eligible

You may qualify if you...

  • Women aged 40 years or older
  • Menopause defined as 12 consecutive months without menses without an alternative medical cause or perimenopause defined as 60 or more days of amenorrhea without an alternative medical cause
  • Patient Health Questionnaire-9 (PHQ-9) pre-treatment score of 5 or higher
  • Ability to determine motor threshold by inducing finger contraction
  • Willingness to abstain from other treatments for depressive symptoms or sexual function during study participation
  • Willingness to comply with study instructions and attend required visits
  • Women of childbearing potential must use birth control during the study
  • Stable psychotherapeutic regime and chronic medications at stable doses for at least 1 month before study entry if applicable
Not Eligible

You will not qualify if you...

  • Presence of metallic objects in or near the head, including conductive, ferromagnetic, or magnetic-sensitive metals
  • Implanted devices such as stimulators, defibrillators, pacemakers, neurostimulators, or electronic implants
  • Use of drug pumps
  • Application of devices in the heart area or HPM-6000UF application in the head area
  • History or tendency to seizures or epilepsy
  • Current anticoagulation therapy
  • Severe or life-threatening conditions including pulmonary insufficiency, heart disorders, and renal insufficiency
  • Decompensated hemorrhagic, blood coagulation, or cardiovascular diseases
  • Presence of malignant or benign tumors
  • Fever or pregnancy
  • Active suicidal intent or history of suicide attempts within last 3 years
  • History or current use of electroconvulsive therapy or vagus nerve stimulation
  • Substance-induced depression or depression due to medical condition
  • Diagnosis of seasonal affective disorder, psychotic disorders, bipolar disorder, or current psychotic symptoms
  • Substance abuse or dependence within past 3 months
  • Neurological disorders such as cerebrovascular disease, brain tumors, cerebral aneurysm, dementia, or movement disorders
  • History of increased intracranial pressure or head trauma
  • Nursing
  • Current or past 12 months intake disorders like bulimia or anorexia
  • Any other condition posing risk or compromising the study at investigator's discretion

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 3 locations

1

Luxury Psychiatry Clinic

Winter Garden, Florida, United States, 34787

Actively Recruiting

2

Aesthetic + Mind MD

Wellesley, Massachusetts, United States, 02481

Actively Recruiting

3

Vitality MD Inc

Toronto, Ontario, Canada, M5M3Y8

Actively Recruiting

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How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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