Actively Recruiting

Phase Not Applicable
Age: 0 - 30Days
All Genders
NCT04365998

BUBOLight®, a New Phototherapy Device for the Treatment of the Newborn's Jaundice

Led by University Hospital, Lille · Updated on 2025-12-23

15

Participants Needed

1

Research Sites

320 weeks

Total Duration

On this page

Sponsors

U

University Hospital, Lille

Lead Sponsor

I

Institut National de la Santé Et de la Recherche Médicale, France

Collaborating Sponsor

AI-Summary

What this Trial Is About

About 50% of full-term newborns and 80% of premature infants develop jaundice which is due to hyperbilirubinemia. In the majority of cases, jaundice disappears naturally without treatment within three weeks of birth, but the bilirubin level may remain too high, which can lead to a serious neurological disease: kernicterus. To avoid this, a therapeutic management must be instituted, and in some cases, one or more phototherapy sessions (PT) may be prescribed. The aim of this trial is to evaluate the safety and level of satisfaction of parents and healthcare team with one innovative device for phototherapy BUBOLight® included two removable strips of luminous textile incorporating optical fibers. 10 newborns requiring phototherapy, will be illuminated during four hours in one session of PT Bilirubin levels is taken at the start of phototherapy H0 and Controls are made at H+6 hours.

CONDITIONS

Official Title

BUBOLight®, a New Phototherapy Device for the Treatment of the Newborn's Jaundice

Who Can Participate

Age: 0 - 30Days
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Infant born after more than 35 weeks of gestation
  • Presence of jaundice confirmed by bilirubin measurement
  • Bilirubin level requiring phototherapy according to national guidelines
  • Weight of at least 2.5 kilograms
  • Infant judged in good health without perinatal asphyxia, antibiotic treatment, or respiratory disorders
  • No feto-maternal rhesus or Kell incompatibility
Not Eligible

You will not qualify if you...

  • Newborn already treated with phototherapy
  • Fever with body temperature above 37.8�C
  • Bilirubin level equal to or exceeding 100 �mol/L above phototherapy indication
  • Jaundice caused by hemolysis or functional/anatomical obstruction
  • Minor relative of investigator
  • Newborn requiring exchange transfusion
  • Presence or family history of congenital erythropoietic porphyria
  • Need for treatments other than phototherapy

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Hop Jeanne de Flandre Chu Lille

Lille, France, 59037

Actively Recruiting

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Research Team

T

Thameur Rakza, MD

CONTACT

S

Serge Mordon, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

1

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