Actively Recruiting
Building Resilience at Schools: Emotional and Biological Assessment and Treatment of Traumatic Stress
Led by Stanford University ยท Updated on 2025-07-18
80800
Participants Needed
3
Research Sites
N/A
Total Duration
On this page
Sponsors
S
Stanford University
Lead Sponsor
P
Pure Edge Inc.
Collaborating Sponsor
AI-Summary
What this Trial Is About
This research focuses on educators and school-aged children in Puerto Rico who have experienced high stress, burnout, and trauma due to natural disasters and the COVID-19 pandemic. The study evaluates two treatment approaches: a mindfulness-based curriculum for educators and students, and Cue-Centered Therapy (CCT) for children showing symptoms of Post Traumatic Stress Disorder (PTSD). Additionally, it aims to explore genetic factors related to resilience by studying gene expression changes before and after interventions. Participants include students, teachers, and counselors who will engage in various interventions. Students receive a mindfulness curriculum in classrooms for 6-8 weeks, while teachers and counselors are trained to deliver mindfulness and CCT treatments. Students with PTSD symptoms during the mindfulness program may undergo 15-18 weeks of CCT. Some students will provide DNA samples before and after interventions to analyze genetic markers linked to resilience. Throughout the study, participants complete surveys at baseline, post-intervention, and follow-up points to assess changes in resilience, anxiety, depression, somatic symptoms, and family functioning. Genetic methylation patterns are also measured. The study monitors the impact of these treatments on psychological well-being and socioemotional development, with research lasting up to 23 weeks for outcome assessments and ongoing genetic analysis.
CONDITIONS
Brief Title
Building Resilience at Schools: Emotional and Biological Assessment and Treatment of Traumatic Stress
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Teachers and students at a participating school site who are willing to participate in the study
- Youth aged 11 to 17 with exposure to at least one DSM-5-defined traumatic event and meeting PTSD symptom criteria per UCLA PTSD scale
- Willingness of youth and caregiver to participate in therapy
- Perpetrator of trauma not living in the home with the child
You will not qualify if you...
- Students currently receiving trauma-focused interventions with a mental health professional
- Low cognitive functioning (IQ less than 70)
- Substance dependence as defined by DSM criteria
- Diagnosis of Autism or Schizophrenia
- Clinically significant medical illness
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - 6 to 8 weeks
Participants will take part in a classroom mindfulness curriculum involving psychoeducation, mindfulness, meditation, and nutrition lessons for well-being.
Daily sessions of 15-20 minutes in the classroom
Duration - 15 to 18 weeks
Students with PTSD symptoms will receive one-on-one trauma-focused therapy with school counselors, including cognitive behavioral and narrative therapy, for 15 to 18 weeks.
Weekly therapy sessions
Duration - 6 to 8 weeks for teachers; 15 to 18 weeks for counselors
Teachers and counselors will be trained to deliver the mindfulness curriculum and trauma therapy, then implement these interventions over several weeks.
Training sessions and implementation visits as scheduled
Duration - Samples collected before and after interventions, up to 23 weeks
Eligible students will provide DNA samples via buccal swabs at up to three time points for genetic analysis related to resilience markers.
2 to 3 sample collection visits
Trial Site Locations
Total: 3 locations
1
Stanford University
Palo Alto, California, United States, 94305
Not Yet Recruiting
2
Centros Sor Isolina Ferre
San Juan, Puerto Rico, Puerto Rico, 00926
Suspended
3
Department of Education Puerto Rico
San Juan, Puerto Rico
Actively Recruiting
Research Team
L
Lab Adminstrator
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NON_RANDOMIZED
Model
SEQUENTIAL
Primary Purpose
TREATMENT
Number of Arms
5
Similar Trials
Frequently Asked Questions
Have more questions? Get in touch with our team for quick support
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here