Frailty as a predictor of surgical outcomes in older patients.
Martin A Makary, Dorry L Segev, Peter J Pronovost...
https://pubmed.ncbi.nlm.nih.gov/20510798Actively Recruiting
Led by The University of Texas Health Science Center, Houston · Updated on 2025-05-01
90
Participants Needed
1
Research Sites
N/A
Total Duration
T
The University of Texas Health Science Center, Houston
Lead Sponsor
N
National Institute on Aging (NIA)
Collaborating Sponsor
Researchers are evaluating the use of Problem Solving Therapy (PST) for older adults undergoing major surgery who have depressive symptoms or feel they lack social support. This pilot study aims to assess how feasible and acceptable it is to deliver PST before and after surgery. The study involves 90 participants recruited at a specialized clinic for older surgical patients. The goal is to gather preliminary data to inform a larger future study on recovery after surgery. Participants are randomly assigned to one of two groups. The intervention group receives nine PST sessions, with 2-3 sessions before surgery and 6-7 sessions afterward via phone or videoconference. PST teaches problem-solving steps such as defining problems, generating solutions, selecting the best options, and monitoring results. The control group receives enhanced usual care consisting of extra mental health education through mailed or emailed handouts. Throughout the study, participants undergo assessments including the World Health Organization Disability Assessment Schedule to measure functional recovery six months after baseline. Depressive symptoms are tracked at three and six months using the Patient Health Questionnaire. Enrollment and consent occur remotely by phone and email. The study carefully monitors participants' progress and collects data to evaluate whether PST can improve post-operative function and mood over time.
CONDITIONS
Building Resilience for Surgical Recovery
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Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
Duration - Approximately 9 weeks covering 2-3 sessions before surgery and 6-7 sessions after surgery
Participants in the intervention arm receive Problem Solving Therapy (PST) through coaching sessions via videoconferencing or phone to develop problem-solving skills before and after surgery. Participants in the control arm receive enhanced usual care through mental health education handouts.
Weekly sessions (remote) for 9 sessions total
Duration - Up to 6 months after baseline
Participants are monitored to assess functional recovery and depressive symptoms after the intervention period.
Follow-up assessments at 3 months and 6 months after baseline
Total: 1 location
1
University of California, San Francisco
San Francisco, California, United States, 94143
Actively Recruiting
J
Jude des Bordes, MBChB, MPH, DrPH, CPH
V
Victoria Tang, MD, MAS
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
PREVENTION
Number of Arms
2
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