Actively Recruiting

Phase Not Applicable
Age: 18Years - 65Years
All Genders
NCT07318181

Building Ukraine's Strength in PTSD Treatment and Research

Led by University of Luxembourg · Updated on 2026-01-15

120

Participants Needed

2

Research Sites

121 weeks

Total Duration

On this page

Sponsors

U

University of Luxembourg

Lead Sponsor

N

National Psychological Association of Ukraine

Collaborating Sponsor

AI-Summary

What this Trial Is About

The Lux4UA project aims to support mental health treatment in Ukraine, especially for those who have experienced traumatic events due to the ongoing conflict and forced displacement. As rates of Post-Traumatic Stress Disorder (PTSD) rise among civilians, military personnel, and refugees, the need for effective trauma care becomes urgent. PTSD is a mental health condition that can develop after experiencing trauma, leading to flashbacks, nightmares, anxiety, and other symptoms that significantly impact daily life. This project introduces an innovative method called the Reconsolidation of Traumatic Memories (RTM) Protocol, which helps individuals reduce distressing memories and trauma-related symptoms. Unlike traditional therapies, the RTM Protocol aims to quickly alleviate PTSD symptoms without requiring patients to relive or discuss in detail their traumatic experiences, which can sometimes be overwhelming. Instead, it employs carefully guided imaginary exercises to help patients reprocess and feel less emotional distress when recalling traumatic memories. This structured approach can lead to significant improvements in just three to five sessions. The Lux4UA project brings together mental health professionals and researchers from Ukraine, Luxembourg, and the United States to test how well this treatment works in Ukraine and to understand if it can be easily integrated into the country's mental health system. By studying the RTM Protocol in three main settings-hospital care and outpatient (walk-in) clinics for veterans and therapy practices for civilians-the project will assess the treatment's effectiveness for people with different needs and backgrounds. It will also evaluate how comfortable and satisfied both mental health practitioners and patients are with the treatment. A key part of the project is training Ukrainian mental health professionals in the RTM Protocol. This training ensures that local mental health professionals are well-prepared to deliver the treatment and support trauma survivors long after the project ends, building a sustainable mental health system in Ukraine. The project will involve careful monitoring of how patients respond to the treatment, paying special attention to their well-being throughout each session. To evaluate the treatment's success, the project will measure changes in PTSD symptoms, as well as signs of anxiety and depression that often accompany trauma. The project will also assess the RTM Protocol's adaptability to Ukrainian needs, seeing if any modifications are necessary to better suit the local context.

CONDITIONS

Official Title

Building Ukraine's Strength in PTSD Treatment and Research

Who Can Participate

Age: 18Years - 65Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Adults aged 18 to 65 years
  • Diagnosed with PTSD by DSM-5-TR or ICD-11 criteria or showing significant PTSD symptoms affecting daily functioning
  • PTSD symptoms cause clinically significant distress or impact social, occupational, or other areas of functioning as measured by the PTSD Checklist (PCL-5)
  • Resident of Ukraine
Not Eligible

You will not qualify if you...

  • Having any other acute comorbid mental health conditions
  • Receiving any other parallel PTSD treatment
  • Unable to provide informed consent, severe cognitive impairment, or unlikely to follow study procedures

AI-Screening

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Trial Site Locations

Total: 2 locations

1

National Psychological Association of Ukraine

Kyiv, Ukraine

Actively Recruiting

2

Veteran Mental Health and Rehabilitation Center 'Forest Glade' Ministry of Health of Ukraine

Kyiv, Ukraine

Actively Recruiting

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Research Team

V

Viktoriia V Gorbunova, ScD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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